C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: syntaxin 1A (brain)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000007207 Stx1a 10090 + 5:135023482-135051100 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005509 Stx1a-001 135023482-135051100 protein_coding
  ENSMUST00000133812 Stx1a-005 135037511-135048830 processed_transcript
  ENSMUST00000144198 Stx1a-004 135041266-135048939 processed_transcript
  ENSMUST00000150838 Stx1a-003 135023560-135051100 nonsense_mediated_decay
  ENSMUST00000156626 Stx1a-002 135041060-135051099 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005509ENSMUST00000133812ENSMUST00000144198ENSMUST00000150838ENSMUST00000156626
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005509 N/A 2.307±0.00 N/A 45.292±23.52 N/A 0.988±0.00 0.254±0.00 0.282±0.06 0.067±0.00 N/A 0.108±0.00 N/A N/A N/A
ENSMUST00000133812 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.550±0.00 N/A N/A
ENSMUST00000144198 N/A N/A N/A N/A N/A 2.672±0.00 N/A N/A N/A N/A 0.202±0.00 N/A N/A N/A
ENSMUST00000150838 3.490±1.20 3.747±0.54 4.052±0.54 5.571±0.00 2.328±0.73 1.417±0.55 0.842±0.31 1.010±0.35 1.632±0.83 2.605±0.56 0.373±0.16 6.831±2.30 1.621±1.03 1.803±0.76
ENSMUST00000156626 N/A 5.444±1.07 N/A N/A N/A 0.554±0.05 N/A N/A 0.362±0.11 N/A 0.320±0.05 8.618±4.35 0.273±0.00 0.632±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000344 CIL_000344_0002 CGP 5:135023482-135064959

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000149 IDA SNARE binding
GO:0001948 ISO glycoprotein binding
GO:0001956 IGI positive regulation of neurotransmitter secretion
GO:0005484 IEA SNAP receptor activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0006886 IEA intracellular protein transport
GO:0008021 IDA synaptic vesicle
GO:0009629 IEA response to gravity
GO:0010807 IGI regulation of synaptic vesicle priming
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016081 IEA synaptic vesicle docking involved in exocytosis
GO:0017022 IEA myosin binding
GO:0017156 IMP calcium ion-dependent exocytosis
GO:0017157 IEA regulation of exocytosis
GO:0019855 IMP calcium channel inhibitor activity
GO:0019904 IEA protein domain specific binding
GO:0030054 IEA cell junction
GO:0030141 IEA secretory granule
GO:0030672 IDA synaptic vesicle membrane
GO:0030674 IEA protein binding, bridging
GO:0031201 ISS SNARE complex
GO:0032028 IEA myosin head/neck binding
GO:0032940 IEA secretion by cell
GO:0042641 IEA actomyosin
GO:0043005 ISO neuron projection
GO:0043008 IEA ATP-dependent protein binding
GO:0043229 IEA intracellular organelle
GO:0043234 IEA protein complex
GO:0045921 IEA positive regulation of exocytosis
GO:0046982 IEA protein heterodimerization activity
GO:0047485 IEA protein N-terminus binding
GO:0048306 IEA calcium-dependent protein binding
GO:0070032 ISO synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
GO:0070033 IEA synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex
GO:0070044 IDA synaptobrevin 2-SNAP-25-syntaxin-1a complex
GO:2000463 IGI positive regulation of excitatory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058994 stx1a syntaxin 1A (brain) protein_coding Danio_rerio
ENSG00000106089 STX1A syntaxin 1A (brain) protein_coding Homo_sapiens

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