C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: actinin, alpha 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000015143 Actn1 10090 - 12:80167542-80260371 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021554 Actn1-201 80167542-80260371 protein_coding
  ENSMUST00000167327 Actn1-202 80168322-80260091 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021554ENSMUST00000167327
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021554 16.160±5.87 3.455±0.56 57.901±6.93 6.016±0.59 11.465±3.33 24.309±3.66 2.325±0.39 5.757±0.85 5.969±3.20 12.850±3.35 0.817±0.40 33.926±6.81 39.849±22.69 1.063±0.30
ENSMUST00000167327 34.405±21.33 1.995±0.08 178.023±34.49 15.834±19.19 10.154±1.68 39.221±6.16 8.129±1.07 6.953±0.68 2.926±1.23 19.952±4.37 1.164±0.37 50.908±13.56 35.183±25.84 2.474±0.80

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002CK CIL_0002CK_0002 CGP 12:80107760-80260371
CIL_0001JZ CIL_0001JZ_0003 CGP 12:80167542-80436601

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001725 TAS stress fiber
GO:0003725 ISO double-stranded RNA binding
GO:0005178 IEA integrin binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0005916 IDA fascia adherens
GO:0005925 TAS focal adhesion
GO:0017166 IEA vinculin binding
GO:0019904 IEA protein domain specific binding
GO:0030018 IDA Z disc
GO:0030141 NAS secretory granule
GO:0030863 TAS cortical cytoskeleton
GO:0030864 IEA cortical actin cytoskeleton
GO:0030865 TAS cortical cytoskeleton organization
GO:0032127 TAS dense core granule membrane
GO:0042803 TAS protein homodimerization activity
GO:0042995 IEA cell projection
GO:0043197 IEA dendritic spine
GO:0044325 IEA ion channel binding
GO:0048041 IEA focal adhesion assembly
GO:0051015 IDA actin filament binding
GO:0051017 IDA actin filament bundle assembly
GO:0051271 IEA negative regulation of cellular component movement
GO:0051764 IEA actin crosslink formation
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007219 actn1 actinin, alpha 1 protein_coding Danio_rerio
ENSG00000072110 ACTN1 actinin, alpha 1 protein_coding Homo_sapiens

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