C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: suppressor of cytokine signaling 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020027 Socs2 10090 - 10:95385362-95417180 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020215 Socs2-001 95411490-95416857 protein_coding
  ENSMUST00000119917 Socs2-008 95412616-95415283 protein_coding
  ENSMUST00000128363 Socs2-004 95413502-95416668 processed_transcript
  ENSMUST00000128854 Socs2-010 95388354-95412734 processed_transcript
  ENSMUST00000129942 Socs2-005 95413062-95416212 protein_coding
  ENSMUST00000130784 Socs2-003 95387667-95392967 retained_intron
  ENSMUST00000134918 Socs2-009 95412420-95414827 processed_transcript
  ENSMUST00000135822 Socs2-012 95413010-95417180 protein_coding
  ENSMUST00000139210 Socs2-002 95385362-95413109 nonsense_mediated_decay
  ENSMUST00000145847 Socs2-006 95415091-95415999 processed_transcript
  ENSMUST00000150432 Socs2-007 95413038-95415484 protein_coding
  ENSMUST00000155148 Socs2-011 95401336-95412994 processed_transcript
  ENSMUST00000170690 Socs2-201 95411490-95416212 protein_coding
  ENSMUST00000172070 Socs2-202 95411490-95415484 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020215ENSMUST00000119917ENSMUST00000129942ENSMUST00000134918ENSMUST00000135822ENSMUST00000139210ENSMUST00000145847ENSMUST00000170690ENSMUST00000172070
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020215 8.019±6.34 11.327±1.17 4.758±1.14 11.693±7.97 12.587±3.53 11.214±1.68 8.488±1.11 13.309±3.57 8.199±6.57 30.872±10.86 2.631±1.29 53.289±14.69 2.416±1.98 0.695±0.32
ENSMUST00000119917 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.674±0.00
ENSMUST00000129942 N/A N/A N/A N/A N/A 6.150±0.00 N/A N/A N/A N/A N/A N/A N/A 1.016±0.02
ENSMUST00000134918 N/A N/A N/A N/A 6.590±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000135822 N/A 10.942±1.21 N/A N/A 17.867±0.54 16.075±2.52 N/A N/A 7.736±2.83 N/A N/A 60.443±7.92 N/A N/A
ENSMUST00000139210 0.405±0.00 N/A 0.602±0.01 2.163±0.03 0.837±0.00 N/A 1.329±0.00 N/A N/A N/A 0.368±0.12 2.602±0.00 N/A 0.009±0.00
ENSMUST00000145847 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 30.925±2.01 N/A 1.123±0.00
ENSMUST00000170690 N/A N/A 1.131±0.00 N/A N/A N/A N/A N/A 0.312±0.00 N/A 2.147±0.00 10.870±5.90 N/A N/A
ENSMUST00000172070 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.277±0.00 39.825±0.63 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004YM CIL_0004YM_0002 CGP 10:95174746-95417180

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0005131 IPI growth hormone receptor binding
GO:0005159 IEA:ISS insulin-like growth factor receptor binding
GO:0005737 IEA cytoplasm
GO:0007595 IGI lactation
GO:0008269 IEA JAK pathway signal transduction adaptor activity
GO:0016567 IEA protein ubiquitination
GO:0035556 IMP intracellular signal transduction
GO:0040014 IMP regulation of multicellular organism growth
GO:0040015 IGI negative regulation of multicellular organism growth
GO:0045666 IDA positive regulation of neuron differentiation
GO:0046426 IGI negative regulation of JAK-STAT cascade
GO:0060749 IGI mammary gland alveolus development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045557 socs2 suppressor of cytokine signaling 2 protein_coding Danio_rerio
ENSG00000120833 SOCS2 suppressor of cytokine signaling 2 protein_coding Homo_sapiens

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