C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Meis homeobox 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020160 Meis1 10090 - 11:18879817-19018985 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000068264 Meis1-001 18880662-19018958 protein_coding
  ENSMUST00000102878 Meis1-004 18880428-19018714 nonsense_mediated_decay
  ENSMUST00000118661 Meis1-006 18880668-19012002 processed_transcript
  ENSMUST00000125722 Meis1-002 18986774-19018922 retained_intron
  ENSMUST00000137300 Meis1-003 19009784-19018922 retained_intron
  ENSMUST00000144988 Meis1-005 18879817-19018985 protein_coding
  ENSMUST00000177357 Meis1-007 18881360-19016289 nonsense_mediated_decay
  ENSMUST00000177417 Meis1-008 18880675-19018714 protein_coding
  ENSMUST00000185131 Meis1-201 18880428-19018969 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000068264ENSMUST00000102878ENSMUST00000118661ENSMUST00000144988ENSMUST00000177357ENSMUST00000177417ENSMUST00000185131
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000068264 6.023±4.37 6.703±1.19 39.127±2.56 9.189±7.26 1.979±0.55 2.639±0.49 3.094±0.18 1.591±0.42 1.459±0.68 9.113±1.88 0.599±0.21 7.711±3.81 1.756±0.94 0.629±0.32
ENSMUST00000102878 N/A 6.838±0.75 N/A N/A 1.341±0.11 1.208±0.22 N/A N/A 0.454±0.00 N/A N/A 4.107±0.00 N/A N/A
ENSMUST00000118661 6.417±4.11 13.055±3.00 27.636±7.37 10.730±4.27 1.727±0.39 2.760±0.49 1.816±0.09 1.704±0.78 1.847±0.94 6.827±1.73 0.449±0.00 12.855±5.09 1.996±0.94 0.474±0.05
ENSMUST00000144988 N/A N/A N/A N/A 0.147±0.00 N/A N/A N/A N/A N/A 0.075±0.00 N/A 0.200±0.00 N/A
ENSMUST00000177357 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.352±0.00 N/A N/A N/A
ENSMUST00000177417 1.762±1.25 N/A 6.507±0.65 1.505±1.24 0.451±0.07 N/A N/A 0.391±0.08 0.374±0.15 2.017±0.01 0.158±0.06 1.733±0.07 0.352±0.20 N/A
ENSMUST00000185131 4.191±2.08 N/A N/A N/A 0.979±0.67 0.973±0.15 N/A 0.954±0.28 N/A 4.770±1.07 N/A 7.748±2.91 0.242±0.00 0.188±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007JR CIL_0007JR_0004 UCNEbase 11:17198316-19679637
CIL_0007XO CIL_0007XO_0002 VISTA 11:18304266-18905268
CIL_00094L CIL_00094L_0002 VISTA 11:18449398-19050623
CIL_000949 CIL_000949_0002 VISTA 11:18616164-19218730
CIL_0008VO CIL_0008VO_0002 VISTA 11:18629400-19230770
CIL_00085V CIL_00085V_0002 VISTA 11:18859805-19461021

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IMP angiogenesis
GO:0002089 IMP lens morphogenesis in camera-type eye
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IC regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0030097 IMP hemopoiesis
GO:0035855 IMP megakaryocyte development
GO:0043565 IDA sequence-specific DNA binding
GO:0045638 IDA negative regulation of myeloid cell differentiation
GO:0045665 IGI negative regulation of neuron differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0048514 IMP blood vessel morphogenesis
GO:0060216 IMP definitive hemopoiesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000143995 MEIS1 Meis homeobox 1 protein_coding Homo_sapiens

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