C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Meis homeobox 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000068264 Meis1-001 ENSMUSG00000020160 10090 - 11:18880662-19018958 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000068264
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000068264 6.023±4.37 6.703±1.19 39.127±2.56 9.189±7.26 1.979±0.55 2.639±0.49 3.094±0.18 1.591±0.42 1.459±0.68 9.113±1.88 0.599±0.21 7.711±3.81 1.756±0.94 0.629±0.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007JR CIL_0007JR_0004 UCNEbase 11:17198316-19679637
CIL_0007XO CIL_0007XO_0002 VISTA 11:18304266-18905268
CIL_00094L CIL_00094L_0002 VISTA 11:18449398-19050623
CIL_000949 CIL_000949_0002 VISTA 11:18616164-19218730
CIL_0008VO CIL_0008VO_0002 VISTA 11:18629400-19230770
CIL_00085V CIL_00085V_0002 VISTA 11:18859805-19461021

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IMP angiogenesis
GO:0002089 IMP lens morphogenesis in camera-type eye
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IC regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0030097 IMP hemopoiesis
GO:0035855 IMP megakaryocyte development
GO:0043565 IDA sequence-specific DNA binding
GO:0045638 IDA negative regulation of myeloid cell differentiation
GO:0045665 IGI negative regulation of neuron differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0048514 IMP blood vessel morphogenesis
GO:0060216 IMP definitive hemopoiesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000102576 meis1-001 protein_coding Danio_rerio 0 1127
ENSDART00000140215 meis1-002 retained_intron Danio_rerio 0 359
ENST00000272369 MEIS1-001 protein_coding Homo_sapiens 0 3843
ENST00000314177 MEIS2-012 nonsense_mediated_decay Homo_sapiens 0 342
ENST00000340545 MEIS2-201 protein_coding Homo_sapiens 0 878
ENST00000397620 MEIS2-005 protein_coding Homo_sapiens 0 800
ENST00000397624 MEIS2-007 protein_coding Homo_sapiens 0 800
ENST00000398506 MEIS1-003 protein_coding Homo_sapiens 0 1845
ENST00000409517 MEIS1-013 processed_transcript Homo_sapiens 0 1716
ENST00000409622 MEIS1-010 processed_transcript Homo_sapiens 0 512
ENST00000424352 MEIS2-003 protein_coding Homo_sapiens 0 815
ENST00000437869 MEIS1-006 protein_coding Homo_sapiens 0 514
ENST00000450027 MEIS1-014 processed_transcript Homo_sapiens 0 601
ENST00000466811 MEIS1-011 processed_transcript Homo_sapiens 0 344
ENST00000475239 MEIS1-012 processed_transcript Homo_sapiens 0 652
ENST00000488550 MEIS1-002 protein_coding Homo_sapiens 0 2220
ENST00000490726 MEIS1-005 processed_transcript Homo_sapiens 0 773
ENST00000491706 MEIS1-008 retained_intron Homo_sapiens 0 1345
ENST00000495021 MEIS1-016 protein_coding Homo_sapiens 0 2839
ENST00000496248 MEIS1-009 processed_transcript Homo_sapiens 0 616
ENST00000498705 MEIS1-007 retained_intron Homo_sapiens 0 697
ENST00000542964 MEIS1-015 processed_transcript Homo_sapiens 0 610
ENST00000557796 MEIS2-017 protein_coding Homo_sapiens 0 880
ENST00000557992 MEIS2-026 retained_intron Homo_sapiens 3.00004e-41 172
ENST00000558643 MEIS2-022 retained_intron Homo_sapiens 3.00004e-41 172
ENST00000559085 MEIS2-008 protein_coding Homo_sapiens 0 793
ENST00000559371 MEIS2-027 retained_intron Homo_sapiens 2.8026e-45 185
ENST00000559408 MEIS2-023 processed_transcript Homo_sapiens 4e-39 165
ENST00000559561 MEIS2-028 protein_coding Homo_sapiens 0 771
ENST00000560281 MEIS1-019 protein_coding Homo_sapiens 0 2765
ENST00000560570 MEIS2-009 nonsense_mediated_decay Homo_sapiens 0 651
ENST00000561264 MEIS2-024 retained_intron Homo_sapiens 0 272
ENST00000561284 MEIS2-025 retained_intron Homo_sapiens 0 344
ENST00000606455 MEIS1-018 processed_transcript Homo_sapiens 0 702

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