C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: notchless homolog 1 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020692 Nle1 10090 - 11:82900768-82908411 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000103213 Nle1-001 82900768-82908411 protein_coding
  ENSMUST00000124109 Nle1-005 82900772-82901816 retained_intron
  ENSMUST00000126202 Nle1-002 82904792-82907687 nonsense_mediated_decay
  ENSMUST00000140318 Nle1-004 82901739-82904268 retained_intron
  ENSMUST00000147915 Nle1-003 82904922-82908342 retained_intron
  ENSMUST00000167196 Nle1-006 82900780-82904289 nonsense_mediated_decay
  ENSMUST00000170815 Nle1-007 82904106-82904636 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000103213ENSMUST00000126202ENSMUST00000140318ENSMUST00000147915ENSMUST00000167196ENSMUST00000170815
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000103213 8.922±2.00 13.611±0.64 5.842±1.33 14.334±3.99 11.437±3.61 11.420±1.34 3.721±0.69 4.259±0.37 9.113±6.77 6.974±0.55 4.343±0.96 19.512±8.37 4.408±3.51
ENSMUST00000126202 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.433±0.00
ENSMUST00000140318 N/A N/A 2.496±0.00 N/A 3.605±0.40 N/A 1.284±0.00 1.148±0.00 1.338±0.18 3.538±0.79 1.002±0.17 9.505±0.00 N/A
ENSMUST00000147915 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.044±0.00
ENSMUST00000167196 N/A N/A N/A N/A N/A N/A N/A 2.283±0.37 N/A N/A 1.818±0.16 16.199±0.00 1.024±0.58
ENSMUST00000170815 N/A N/A N/A N/A 8.800±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006ES CIL_0006ES_0002 CGP 11:82876434-82900801
CIL_0003B9 CIL_0003B9_0002 CGP 11:82892124-82908411
CIL_0003K1 CIL_0003K1_0002 CGP 11:82900768-82943403

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001826 IMP inner cell mass cell differentiation
GO:0003674 ND molecular_function
GO:0005634 IEA nucleus
GO:0005730 IDA nucleolus
GO:0007219 IDA Notch signaling pathway
GO:0042273 IMP ribosomal large subunit biogenesis
GO:0045930 IMP negative regulation of mitotic cell cycle
GO:0061484 IMP hematopoietic stem cell homeostasis
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway
GO:2001268 IMP negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057105 nle1 notchless homolog 1 (Drosophila) protein_coding Danio_rerio
ENSG00000073536 NLE1 notchless homolog 1 (Drosophila) protein_coding Homo_sapiens

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