C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: notchless homolog 1 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000073536 NLE1 9606 - 17:35128753-35142315 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360831 NLE1-005 35132071-35142303 protein_coding
  ENST00000442241 NLE1-001 35131347-35142315 protein_coding
  ENST00000586869 NLE1-004 35128753-35142284 protein_coding
  ENST00000588019 NLE1-003 35132244-35137167 protein_coding
  ENST00000588642 NLE1-007 35137053-35142297 nonsense_mediated_decay
  ENST00000589367 NLE1-002 35136367-35142304 nonsense_mediated_decay
  ENST00000593176 NLE1-008 35137024-35142233 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360831ENST00000442241ENST00000586869ENST00000588019ENST00000588642ENST00000589367
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360831 1.671±0.00 N/A N/A N/A 1.564±0.00 1.238±0.99 0.154±0.03 0.272±0.00 1.343±0.00 1.364±0.00 1.971±0.00 3.466±0.48 2.356±0.79 N/A
ENST00000442241 1.892±0.00 3.774±0.00 0.031±0.00 1.177±0.48 2.496±0.00 1.627±0.00 0.344±0.00 2.214±0.00 1.214±0.00 0.812±0.00 2.486±0.00 2.937±1.41 2.420±0.90 N/A
ENST00000586869 N/A N/A N/A 1.130±0.00 N/A 0.622±0.00 0.066±0.00 0.108±0.00 0.351±0.00 0.151±0.00 N/A 1.527±0.22 N/A 1.352±0.00
ENST00000588019 N/A N/A N/A N/A 2.179±0.00 2.174±0.00 N/A N/A 0.920±0.00 0.767±0.00 2.614±0.00 N/A 2.005±0.00 N/A
ENST00000588642 N/A N/A 0.200±0.00 N/A N/A 1.043±0.00 0.862±0.00 1.379±0.00 N/A N/A 2.535±0.00 N/A N/A N/A
ENST00000589367 N/A N/A N/A N/A N/A N/A 0.304±0.00 N/A 1.650±0.00 N/A N/A 1.204±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006ES CIL_0006ES_0001 CGP 17:35092208-35130732
CIL_0003B9 CIL_0003B9_0001 CGP 17:35121579-35142315
CIL_0003K1 CIL_0003K1_0001 CGP 17:35128753-35189345

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001826 IEA inner cell mass cell differentiation
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0007219 IEA Notch signaling pathway
GO:0042273 IEA ribosomal large subunit biogenesis
GO:0045930 IEA negative regulation of mitotic cell cycle
GO:0061484 IEA hematopoietic stem cell homeostasis
GO:0090263 IEA positive regulation of canonical Wnt signaling pathway
GO:2001268 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057105 nle1 notchless homolog 1 (Drosophila) protein_coding Danio_rerio
ENSMUSG00000020692 Nle1 notchless homolog 1 (Drosophila) protein_coding Mus_musculus

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