C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ligase III, DNA, ATP-dependent
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020697 Lig3 10090 + 11:82781108-82804274 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021039 Lig3-201 82781135-82804274 protein_coding
  ENSMUST00000080461 Lig3-002 82781185-82800653 protein_coding
  ENSMUST00000092849 Lig3-001 82781108-82802862 protein_coding
  ENSMUST00000131537 Lig3-008 82781198-82790305 protein_coding
  ENSMUST00000154887 Lig3-003 82797218-82799567 retained_intron
  ENSMUST00000155818 Lig3-005 82795685-82799550 retained_intron
  ENSMUST00000172609 Lig3-010 82781142-82796541 retained_intron
  ENSMUST00000172837 Lig3-012 82798349-82804274 protein_coding
  ENSMUST00000173009 Lig3-006 82781198-82790304 protein_coding
  ENSMUST00000173347 Lig3-007 82781193-82802025 protein_coding
  ENSMUST00000173722 Lig3-009 82781203-82804198 protein_coding
  ENSMUST00000173727 Lig3-011 82781193-82802026 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000080461ENSMUST00000092849ENSMUST00000155818ENSMUST00000173347ENSMUST00000173727
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000080461 N/A 3.032±0.69 N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.857±1.55 N/A 33.933±9.47
ENSMUST00000092849 4.081±0.02 2.113±0.75 4.850±0.70 5.585±2.42 3.270±1.23 N/A 1.816±0.25 2.357±0.78 3.616±0.99 2.242±0.45 3.572±0.66 6.659±2.09 6.157±0.54 8.517±0.08
ENSMUST00000155818 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 117.059±0.00
ENSMUST00000173347 N/A 2.842±0.00 N/A 3.900±0.38 3.101±0.00 4.294±0.52 1.563±0.32 2.822±0.76 3.217±0.01 2.182±0.07 2.020±0.33 5.234±1.62 7.311±2.73 16.367±2.08
ENSMUST00000173727 6.110±0.37 2.004±0.28 N/A N/A 4.027±0.00 3.695±0.33 N/A 2.198±0.00 2.810±0.59 2.793±0.00 2.060±0.00 5.335±1.61 7.730±1.02 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00055Q CIL_00055Q_0002 CGP 11:82764345-82804274
CIL_00055O CIL_00055O_0002 CGP 11:82781108-82871210

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000794 IDA condensed nuclear chromosome
GO:0000795 IDA synaptonemal complex
GO:0003677 IEA DNA binding
GO:0003909 IEA DNA ligase activity
GO:0003910 IBA DNA ligase (ATP) activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IBA nucleus
GO:0005694 IBA chromosome
GO:0006266 IBA DNA ligation
GO:0006273 IBA lagging strand elongation
GO:0006288 IEA base-excision repair, DNA ligation
GO:0006289 IBA nucleotide-excision repair
GO:0006303 IMP double-strand break repair via nonhomologous end joining
GO:0006310 IEA DNA recombination
GO:0007049 IEA cell cycle
GO:0008270 IEA zinc ion binding
GO:0043504 IMP mitochondrial DNA repair
GO:0045910 IMP negative regulation of DNA recombination
GO:0051103 IEA DNA ligation involved in DNA repair
GO:0051301 IEA cell division
GO:0071897 IEA DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052553 lig3 ligase III, DNA, ATP-dependent protein_coding Danio_rerio
ENSG00000005156 LIG3 ligase III, DNA, ATP-dependent protein_coding Homo_sapiens

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