C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ligase III, DNA, ATP-dependent
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000005156 LIG3 9606 + 17:34980494-35009743 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262327 LIG3-002 34980546-35003172 protein_coding
  ENST00000378526 LIG3-001 34980494-35009743 protein_coding
  ENST00000585370 LIG3-015 34997756-34998671 nonsense_mediated_decay
  ENST00000585740 LIG3-007 34980559-34992607 protein_coding
  ENST00000585941 LIG3-005 34980512-34994429 protein_coding
  ENST00000586058 LIG3-012 34994187-34998254 retained_intron
  ENST00000586119 LIG3-014 34997718-35001293 retained_intron
  ENST00000586407 LIG3-008 34980640-34989540 processed_transcript
  ENST00000586435 LIG3-010 34986094-34991314 retained_intron
  ENST00000588109 LIG3-009 34983452-34991065 nonsense_mediated_decay
  ENST00000588713 LIG3-013 34994275-34996373 retained_intron
  ENST00000590181 LIG3-004 34980577-34989880 retained_intron
  ENST00000590630 LIG3-011 34991637-34997825 retained_intron
  ENST00000592244 LIG3-016 35002834-35004372 retained_intron
  ENST00000592690 LIG3-006 34980558-34989657 protein_coding
  ENST00000593099 LIG3-003 34997034-35004804 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaENST00000262327ENST00000378526ENST00000585941ENST00000586119ENST00000590181
Transcript ID Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta
ENST00000262327 2.021±0.00 N/A N/A 3.680±0.00 2.051±0.99 2.302±0.00 4.255±0.00 5.587±0.00 7.076±1.35 6.259±0.62
ENST00000378526 0.742±0.00 1.248±0.00 1.206±0.00 1.154±0.00 N/A 1.216±0.00 1.029±0.00 1.184±0.00 2.186±0.14 N/A
ENST00000585941 N/A N/A N/A N/A 1.657±0.00 N/A N/A N/A N/A N/A
ENST00000586119 N/A N/A N/A N/A N/A N/A N/A 7.449±0.00 N/A N/A
ENST00000590181 N/A N/A N/A 7.859±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00055V CIL_00055V_0001 CGP 17:34580749-34981078
CIL_000745 CIL_000745_0001 CGP 17:34927859-34981078
CIL_00055Q CIL_00055Q_0001 CGP 17:34961530-35009743
CIL_00055O CIL_00055O_0001 CGP 17:34980494-35089319

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000794 IEA condensed nuclear chromosome
GO:0000795 IEA synaptonemal complex
GO:0003677 IEA DNA binding
GO:0003909 IDA DNA ligase activity
GO:0003910 IEA:IBA DNA ligase (ATP) activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005694 IBA chromosome
GO:0006273 IBA lagging strand elongation
GO:0006281 TAS:IEA DNA repair
GO:0006284 TAS base-excision repair
GO:0006288 IEA base-excision repair, DNA ligation
GO:0006289 IBA nucleotide-excision repair
GO:0006303 IEA double-strand break repair via nonhomologous end joining
GO:0006310 IEA DNA recombination
GO:0007131 TAS reciprocal meiotic recombination
GO:0007283 TAS spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0043504 IEA mitochondrial DNA repair
GO:0045910 IEA negative regulation of DNA recombination
GO:0051103 IEA DNA ligation involved in DNA repair
GO:0071897 IEA DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052553 lig3 ligase III, DNA, ATP-dependent protein_coding Danio_rerio
ENSMUSG00000020697 Lig3 ligase III, DNA, ATP-dependent protein_coding Mus_musculus

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