C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022216 Psme1 10090 + 14:55578123-55581529 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000089619 Psme1-012 55578575-55581381 protein_coding
  ENSMUST00000172738 Psme1-003 55578575-55581381 protein_coding
  ENSMUST00000172941 Psme1-004 55578405-55580642 retained_intron
  ENSMUST00000173113 Psme1-008 55580034-55580947 retained_intron
  ENSMUST00000173388 Psme1-005 55578486-55580403 retained_intron
  ENSMUST00000173544 Psme1-002 55578456-55581528 retained_intron
  ENSMUST00000174148 Psme1-007 55579964-55581451 retained_intron
  ENSMUST00000174259 Psme1-001 55578360-55581528 protein_coding
  ENSMUST00000174419 Psme1-009 55580748-55581529 nonsense_mediated_decay
  ENSMUST00000174484 Psme1-006 55578123-55581346 protein_coding
  ENSMUST00000174563 Psme1-010 55578538-55580942 protein_coding
  ENSMUST00000174791 Psme1-011 55578468-55581374 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000089619ENSMUST00000172941ENSMUST00000173388ENSMUST00000174148ENSMUST00000174259ENSMUST00000174419ENSMUST00000174484ENSMUST00000174563
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000089619 N/A N/A N/A 14.430±0.00 N/A N/A N/A N/A N/A N/A N/A 57.588±0.00 14.719±0.75 2.977±0.00
ENSMUST00000172941 N/A 28.024±3.82 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000173388 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 55.940±0.00 23.298±2.79 6.711±0.00
ENSMUST00000174148 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 35.792±17.94 N/A N/A
ENSMUST00000174259 29.105±8.62 28.203±9.46 60.728±1.44 28.264±14.63 24.198±4.78 12.560±1.87 30.922±2.71 17.942±2.64 30.807±16.72 20.917±1.32 19.170±2.43 24.574±12.91 20.752±7.32 2.648±0.39
ENSMUST00000174419 N/A N/A N/A 30.851±0.00 52.763±0.00 N/A N/A N/A N/A N/A N/A 109.090±0.00 51.938±4.79 N/A
ENSMUST00000174484 23.979±3.22 27.508±2.03 N/A N/A 33.280±9.94 24.343±3.71 13.855±2.16 12.828±2.21 13.932±2.94 29.016±2.30 N/A 24.850±4.18 14.463±5.65 1.967±0.36
ENSMUST00000174563 N/A N/A N/A N/A 46.122±0.00 N/A N/A N/A 29.062±0.00 N/A N/A 111.363±7.44 N/A 1.923±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00037E CIL_00037E_0002 CGP 14:55575617-55581529
CIL_00031C CIL_00031C_0002 CGP 14:55578123-55585302

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0008537 IEA proteasome activator complex
GO:0010950 IPI positive regulation of endopeptidase activity
GO:0019884 IMP antigen processing and presentation of exogenous antigen
GO:0061133 IPI endopeptidase activator activity
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002165 psme1 proteasome activator subunit 1 protein_coding Danio_rerio
ENSG00000092010 PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) protein_coding Homo_sapiens

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