C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: vitamin D receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022479 Vdr 10090 - 15:97854425-97910630 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023119 Vdr-001 97854425-97908310 protein_coding
  ENSMUST00000126568 Vdr-002 97876776-97896813 protein_coding
  ENSMUST00000139656 Vdr-003 97857537-97859698 retained_intron
  ENSMUST00000173104 Vdr-006 97876848-97910630 protein_coding
  ENSMUST00000173611 Vdr-005 97884889-97909562 protein_coding
  ENSMUST00000174633 Vdr-004 97884877-97910630 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023119ENSMUST00000126568ENSMUST00000139656
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023119 0.466±0.26 2.542±1.04 0.548±0.01 0.064±0.06 3.148±0.29 79.808±3.38 0.628±0.19 41.876±5.19 0.024±0.01 2.214±0.20 0.039±0.03 1.377±0.32 1.717±0.96 1.503±0.41
ENSMUST00000126568 N/A N/A N/A 0.051±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000139656 N/A N/A N/A 0.019±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003DI CIL_0003DI_0003 CGP 15:97792664-97910630
CIL_0005YK CIL_0005YK_0002 CGP 15:97854425-97970286

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000902 IEA cell morphogenesis
GO:0001501 IMP skeletal system development
GO:0003677 ISO DNA binding
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006816 IMP calcium ion transport
GO:0006874 IMP cellular calcium ion homeostasis
GO:0007275 IMP multicellular organismal development
GO:0007595 IMP lactation
GO:0008270 IEA zinc ion binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0008434 IEA calcitriol receptor activity
GO:0009887 IMP organ morphogenesis
GO:0010628 IEA positive regulation of gene expression
GO:0010839 IEA negative regulation of keratinocyte proliferation
GO:0010980 IEA positive regulation of vitamin D 24-hydroxylase activity
GO:0030522 IDA intracellular receptor signaling pathway
GO:0038183 IEA bile acid signaling pathway
GO:0038186 IEA lithocholic acid receptor activity
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045618 IEA positive regulation of keratinocyte differentiation
GO:0045892 ISO negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046697 IEA decidualization
GO:0046965 IEA retinoid X receptor binding
GO:0050892 IMP intestinal absorption
GO:0060058 IMP positive regulation of apoptotic process involved in mammary gland involution
GO:0060558 IMP regulation of calcidiol 1-monooxygenase activity
GO:0060745 IMP mammary gland branching involved in pregnancy
GO:0070561 IEA vitamin D receptor signaling pathway
GO:0070644 IEA vitamin D response element binding
GO:1902098 IEA calcitriol binding
GO:1902121 IEA lithocholic acid binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043059 VDR (1 of 2) vitamin D (1,25- dihydroxyvitamin D3) receptor protein_coding Danio_rerio
ENSDARG00000070721 vdrb vitamin D receptor b protein_coding Danio_rerio
ENSG00000111424 VDR vitamin D (1,25- dihydroxyvitamin D3) receptor protein_coding Homo_sapiens

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