C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM domain and actin binding 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023022 Lima1 10090 - 15:99778470-99875428 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000073691 Lima1-001 99778470-99875428 protein_coding
  ENSMUST00000109024 Lima1-003 99778470-99820143 protein_coding
  ENSMUST00000171450 Lima1-002 99841228-99875416 retained_intron
  ENSMUST00000172119 Lima1-004 99781239-99783973 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000073691ENSMUST00000109024
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000073691 7.106±3.78 5.342±1.42 14.213±0.43 2.110±1.35 3.606±0.90 48.136±3.60 1.394±0.33 13.586±0.52 5.957±3.55 9.441±0.99 0.592±0.24 4.514±1.47 17.557±10.71 1.284±0.55
ENSMUST00000109024 10.865±4.21 2.468±0.00 47.552±1.33 3.945±0.82 7.907±1.32 N/A 2.488±0.56 3.981±0.63 1.882±0.41 7.221±1.10 1.161±0.30 9.063±3.76 21.299±7.19 0.377±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PE CIL_0008PE_0002 VISTA 15:99507076-100109694
CIL_0008CC CIL_0008CC_0002 VISTA 15:99507743-100109214
CIL_0000LJ CIL_0000LJ_0002 CGP 15:99734881-99875428
CIL_00051T CIL_00051T_0002 CGP 15:99778470-99967075

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001725 ISS stress fiber
GO:0003785 ISS actin monomer binding
GO:0005925 ISS focal adhesion
GO:0008270 IEA zinc ion binding
GO:0015629 IDA actin cytoskeleton
GO:0030835 ISS negative regulation of actin filament depolymerization
GO:0031529 ISS ruffle organization
GO:0051015 ISS actin filament binding
GO:0051017 ISS actin filament bundle assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074020 lima1 LIM domain and actin binding 1 protein_coding Danio_rerio
ENSDARG00000076009 LIMA1 (2 of 2) LIM domain and actin binding 1 protein_coding Danio_rerio
ENSG00000050405 LIMA1 LIM domain and actin binding 1 protein_coding Homo_sapiens

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