C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: slit homolog 1 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025020 Slit1 10090 - 19:41600257-41743665 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025993 Slit1-001 41600259-41743665 protein_coding
  ENSMUST00000166496 Slit1-004 41600451-41743492 protein_coding
  ENSMUST00000169141 Slit1-002 41600257-41743492 protein_coding
  ENSMUST00000169416 Slit1-005 41604369-41608530 retained_intron
  ENSMUST00000171586 Slit1-003 41646103-41743486 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025993ENSMUST00000166496ENSMUST00000169141ENSMUST00000169416
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025993 N/A 0.979±0.23 N/A 5.038±0.00 0.043±0.01 0.096±0.02 0.008±0.00 0.044±0.02 0.064±0.06 0.017±0.01 N/A 0.236±0.08 5.228±7.15 N/A
ENSMUST00000166496 0.045±0.00 N/A 0.016±0.00 4.058±0.00 0.047±0.02 N/A N/A 0.005±0.00 0.021±0.00 N/A N/A 0.096±0.05 26.017±0.00 0.650±0.00
ENSMUST00000169141 0.047±0.02 2.845±1.36 0.031±0.01 7.987±3.21 0.100±0.03 0.226±0.12 0.021±0.01 0.022±0.01 0.055±0.03 0.042±0.02 0.186±0.05 0.263±0.07 6.193±6.27 0.141±0.00
ENSMUST00000169416 N/A N/A N/A N/A N/A N/A N/A 0.113±0.00 0.147±0.00 N/A 0.358±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008SO CIL_0008SO_0002 VISTA 19:41258217-41859329
CIL_0003F3 CIL_0003F3_0002 CGP 19:41600257-41802084

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 TAS receptor binding
GO:0005509 IEA calcium ion binding
GO:0005615 IDA extracellular space
GO:0007409 IDA axonogenesis
GO:0007411 IGI axon guidance
GO:0007420 IEA brain development
GO:0008045 IEA motor neuron axon guidance
GO:0021510 IEA spinal cord development
GO:0021772 IGI olfactory bulb development
GO:0022028 IMP tangential migration from the subventricular zone to the olfactory bulb
GO:0022029 IGI telencephalon cell migration
GO:0031290 IGI retinal ganglion cell axon guidance
GO:0033563 IGI dorsal/ventral axon guidance
GO:0040023 IDA establishment of nucleus localization
GO:0043395 IEA heparan sulfate proteoglycan binding
GO:0048495 IPI Roundabout binding
GO:0048812 IGI neuron projection morphogenesis
GO:0048843 IEA negative regulation of axon extension involved in axon guidance
GO:0048846 IEA axon extension involved in axon guidance
GO:0050919 IMP negative chemotaxis
GO:0051964 ISS negative regulation of synapse assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039528 slit1b slit homolog 1b (Drosophila) protein_coding Danio_rerio
ENSDARG00000044954 slit1a slit homolog 1a (Drosophila) protein_coding Danio_rerio
ENSG00000187122 SLIT1 slit homolog 1 (Drosophila) protein_coding Homo_sapiens

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