C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: activating transcription factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027104 Atf2 10090 - 2:73816509-73892639 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055833 Atf2-005 73816509-73892614 protein_coding
  ENSMUST00000090802 Atf2-006 73816509-73892612 protein_coding
  ENSMUST00000100009 Atf2-201 73816524-73863290 protein_coding
  ENSMUST00000112007 Atf2-002 73816509-73892631 protein_coding
  ENSMUST00000112010 Atf2-008 73816509-73892536 protein_coding
  ENSMUST00000112016 Atf2-001 73816509-73892639 protein_coding
  ENSMUST00000112017 Atf2-202 73818266-73892555 protein_coding
  ENSMUST00000124737 Atf2-015 73816509-73845505 protein_coding
  ENSMUST00000125159 Atf2-009 73862969-73892628 processed_transcript
  ENSMUST00000128531 Atf2-011 73845440-73892553 protein_coding
  ENSMUST00000129555 Atf2-014 73845734-73850604 processed_transcript
  ENSMUST00000136958 Atf2-013 73829801-73892530 protein_coding
  ENSMUST00000138098 Atf2-010 73862876-73892594 processed_transcript
  ENSMUST00000141050 Atf2-003 73844869-73892628 processed_transcript
  ENSMUST00000143714 Atf2-004 73826359-73892613 processed_transcript
  ENSMUST00000154456 Atf2-016 73845439-73892593 protein_coding
  ENSMUST00000154965 Atf2-012 73873274-73892550 processed_transcript
  ENSMUST00000156455 Atf2-007 73816520-73892628 processed_transcript
  ENSMUST00000173010 Atf2-017 73818822-73863238 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000055833ENSMUST00000090802ENSMUST00000100009ENSMUST00000112007ENSMUST00000112010ENSMUST00000112016ENSMUST00000112017ENSMUST00000124737ENSMUST00000128531ENSMUST00000143714ENSMUST00000173010
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000055833 2.551±0.68 N/A 1.968±0.00 3.122±0.00 2.969±0.00 N/A 1.468±0.51 1.662±0.53 1.221±0.00 3.839±0.80 0.421±0.01 2.601±0.00 2.777±0.00 N/A
ENSMUST00000090802 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.646±0.00 N/A N/A N/A
ENSMUST00000100009 3.120±0.35 3.166±1.32 3.840±0.00 6.045±3.53 2.552±1.21 3.213±1.30 0.837±0.13 2.735±1.26 1.988±0.61 2.551±0.80 0.808±0.20 4.655±1.28 3.994±2.23 N/A
ENSMUST00000112007 1.341±0.00 2.112±0.92 1.206±0.00 N/A N/A 1.817±0.25 1.049±0.35 2.260±0.41 0.689±0.09 3.131±1.48 0.746±0.08 1.748±0.00 1.760±0.00 3.140±1.59
ENSMUST00000112010 0.941±0.00 N/A N/A N/A 1.694±0.58 N/A 1.386±0.21 1.482±0.10 1.540±0.50 1.820±0.00 1.353±0.65 2.951±1.37 4.001±1.52 2.726±0.24
ENSMUST00000112016 N/A N/A 2.091±0.55 4.413±1.42 N/A N/A N/A N/A 1.219±0.00 N/A 0.742±0.20 3.079±0.79 1.712±0.30 N/A
ENSMUST00000112017 N/A N/A N/A 5.488±0.00 N/A N/A N/A N/A N/A N/A N/A 4.617±0.00 4.353±1.24 2.641±0.38
ENSMUST00000124737 N/A N/A 2.648±0.00 4.187±1.20 N/A N/A N/A N/A 2.478±0.57 N/A N/A 3.357±1.26 3.481±0.81 N/A
ENSMUST00000128531 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.712±0.00 N/A
ENSMUST00000143714 N/A N/A N/A N/A 1.922±0.00 N/A N/A N/A N/A N/A N/A 1.710±0.56 N/A N/A
ENSMUST00000173010 N/A 1.819±0.42 N/A N/A 2.721±0.91 2.103±0.46 N/A 2.572±0.00 1.112±0.00 2.582±0.00 N/A N/A N/A 11.938±2.70

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001HB CIL_0001HB_0002 CGP 2:73610660-73892639
CIL_0001H6 CIL_0001H6_0002 CGP 2:73816509-73911326

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001102 IEA RNA polymerase II activating transcription factor binding
GO:0003151 IMP outflow tract morphogenesis
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 ISO sequence-specific DNA binding transcription factor activity
GO:0004402 ISS histone acetyltransferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 ISS cytoplasm
GO:0005741 ISS mitochondrial outer membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0006970 ISS response to osmotic stress
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0008140 IEA cAMP response element binding protein binding
GO:0016020 IDA membrane
GO:0016573 IEA histone acetylation
GO:0019901 IEA protein kinase binding
GO:0031573 ISS intra-S DNA damage checkpoint
GO:0032915 IMP positive regulation of transforming growth factor beta2 production
GO:0035497 IEA cAMP response element binding
GO:0035861 ISS site of double-strand break
GO:0043565 IEA sequence-specific DNA binding
GO:0045444 IGI fat cell differentiation
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0051091 ISS positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060612 IGI adipose tissue development
GO:1902110 ISS positive regulation of mitochondrial membrane permeability involved in apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023903 atf2 activating transcription factor 2 protein_coding Danio_rerio
ENSG00000115966 ATF2 activating transcription factor 2 protein_coding Homo_sapiens

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