C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: short stature homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027833 Shox2 10090 - 3:66971727-66981771 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029422 Shox2-001 66972790-66981771 protein_coding
  ENSMUST00000162060 Shox2-004 66972780-66978447 protein_coding
  ENSMUST00000162098 Shox2-002 66971727-66981318 protein_coding
  ENSMUST00000162439 Shox2-003 66973259-66981141 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastHeartOvaryENSMUST00000029422ENSMUST00000162060ENSMUST00000162098ENSMUST00000162439
Transcript ID Adrenal Brain Breast Heart Ovary
ENSMUST00000029422 0.315±0.05 5.425±0.73 N/A N/A N/A
ENSMUST00000162060 0.480±0.15 N/A N/A N/A 0.284±0.00
ENSMUST00000162098 N/A 9.536±5.21 2.303±0.88 0.432±0.15 0.471±0.00
ENSMUST00000162439 0.934±0.11 N/A 5.473±0.86 0.619±0.00 0.300±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SK CIL_0007SK_0002 VISTA 3:66400786-67001918
CIL_0008TK CIL_0008TK_0002 VISTA 3:66634735-67237240
CIL_0007KJ CIL_0007KJ_0002 UCNEbase 3:66683972-67341053
CIL_00098J CIL_00098J_0002 VISTA 3:66709377-67310623
CIL_0007SC CIL_0007SC_0002 VISTA 3:66736007-67337651
CIL_0008QV CIL_0008QV_0002 VISTA 3:66770295-67371594
CIL_0008BN CIL_0008BN_0002 VISTA 3:66846973-67447795
CIL_00086V CIL_00086V_0002 VISTA 3:66870618-67471970
CIL_0008BM CIL_0008BM_0002 VISTA 3:66890932-67492590
CIL_0008KO CIL_0008KO_0002 VISTA 3:66912683-67513884
CIL_0004JW CIL_0004JW_0003 CGP 3:66971727-67358396

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001649 IMP osteoblast differentiation
GO:0002053 IMP positive regulation of mesenchymal cell proliferation
GO:0002062 IMP chondrocyte differentiation
GO:0002063 IMP chondrocyte development
GO:0003170 IMP heart valve development
GO:0003209 IMP cardiac atrium morphogenesis
GO:0005634 IEA nucleus
GO:0030326 IMP embryonic limb morphogenesis
GO:0032330 IMP regulation of chondrocyte differentiation
GO:0035115 IMP embryonic forelimb morphogenesis
GO:0043565 IEA sequence-specific DNA binding
GO:0045880 IMP positive regulation of smoothened signaling pathway
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048557 IMP embryonic digestive tract morphogenesis
GO:0048598 IMP embryonic morphogenesis
GO:0048743 IMP positive regulation of skeletal muscle fiber development
GO:0050772 IMP positive regulation of axonogenesis
GO:0060272 IMP embryonic skeletal joint morphogenesis
GO:0060351 IMP cartilage development involved in endochondral bone morphogenesis
GO:0060415 IMP muscle tissue morphogenesis
GO:2000172 IMP regulation of branching morphogenesis of a nerve

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075713 shox2 short stature homeobox 2 protein_coding Danio_rerio
ENSG00000168779 SHOX2 short stature homeobox 2 protein_coding Homo_sapiens

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