C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: valosin containing protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028452 Vcp 10090 - 4:42979963-43000507 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030164 Vcp-001 42979963-43000507 protein_coding
  ENSMUST00000139843 Vcp-003 42992735-42993758 processed_transcript
  ENSMUST00000148182 Vcp-002 42993712-43000433 processed_transcript
  ENSMUST00000154423 Vcp-005 42986242-42989330 processed_transcript
  ENSMUST00000154541 Vcp-004 42984366-42985821 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030164ENSMUST00000148182ENSMUST00000154541
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030164 51.198±5.45 44.913±4.49 56.812±4.16 49.773±26.15 55.820±17.33 43.938±7.59 46.210±12.61 56.111±11.64 58.767±12.86 62.508±1.93 108.914±5.28 95.698±26.15 85.044±41.32 38.397±13.75
ENSMUST00000148182 N/A 198.833±86.88 N/A N/A 212.825±9.05 124.926±45.59 N/A 94.613±0.00 59.361±23.61 120.187±6.77 N/A 260.468±75.93 N/A N/A
ENSMUST00000154541 N/A N/A N/A 21.118±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 29.476±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002PW CIL_0002PW_0002 CGP 4:42949814-42983640
CIL_0005SG CIL_0005SG_0002 CGP 4:42969604-43000507
CIL_0005SF CIL_0005SF_0002 CGP 4:42979963-43010506

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000502 IEA proteasome complex
GO:0000836 IEA Hrd1p ubiquitin ligase complex
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005783 ISS endoplasmic reticulum
GO:0005789 IEA endoplasmic reticulum membrane
GO:0005811 IEA lipid particle
GO:0005829 ISS cytosol
GO:0006200 IEA ATP catabolic process
GO:0006302 ISS double-strand break repair
GO:0006511 IGI ubiquitin-dependent protein catabolic process
GO:0006888 IEA ER to Golgi vesicle-mediated transport
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0008289 IEA lipid binding
GO:0016567 ISS protein ubiquitination
GO:0018279 ISS protein N-linked glycosylation via asparagine
GO:0019903 IEA protein phosphatase binding
GO:0019904 IEA protein domain specific binding
GO:0019985 ISS translesion synthesis
GO:0030433 ISS ER-associated ubiquitin-dependent protein catabolic process
GO:0030970 ISS retrograde protein transport, ER to cytosol
GO:0031334 IEA positive regulation of protein complex assembly
GO:0031593 IDA polyubiquitin binding
GO:0032403 IEA protein complex binding
GO:0032436 IEA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034214 IEA protein hexamerization
GO:0035800 IEA deubiquitinase activator activity
GO:0035861 ISS site of double-strand break
GO:0042802 IEA identical protein binding
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043234 IPI protein complex
GO:0043531 IEA ADP binding
GO:0044822 IEA poly(A) RNA binding
GO:0045732 IEA positive regulation of protein catabolic process
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051260 IEA protein homooligomerization
GO:0070062 IEA extracellular vesicular exosome
GO:0070842 IGI aggresome assembly
GO:1903006 IEA positive regulation of protein K63-linked deubiquitination
GO:1903007 IEA positive regulation of Lys63-specific deubiquitinase activity
GO:1990381 IEA ubiquitin-specific protease binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020008 vcp valosin containing protein protein_coding Danio_rerio
ENSG00000165280 VCP valosin containing protein protein_coding Homo_sapiens

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