C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear receptor co-repressor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000086083 Ncor2-004 ENSMUSG00000029478 10090 - 5:125017162-125179053 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000086083
Transcript ID Adipose Adrenal Brain Breast Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000086083 0.620±0.00 3.469±0.00 7.378±6.05 1.328±0.66 0.648±0.00 0.598±0.02 0.640±0.31 2.235±0.36 7.275±6.66 4.646±0.00 1.032±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004PN CIL_0004PN_0002 CGP 5:125003447-125179219
CIL_000399 CIL_000399_0002 CGP 5:125017153-125341094

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000118 IDA histone deacetylase complex
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IEA chromatin
GO:0001012 IEA RNA polymerase II regulatory region DNA binding
GO:0001701 IMP in utero embryonic development
GO:0003007 IGI heart morphogenesis
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003714 IMP transcription corepressor activity
GO:0005112 IEA Notch binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0007595 IEA lactation
GO:0010243 IEA response to organonitrogen compound
GO:0016020 IEA membrane
GO:0016363 IEA nuclear matrix
GO:0016604 IDA nuclear body
GO:0016922 IEA ligand-dependent nuclear receptor binding
GO:0017053 IEA transcriptional repressor complex
GO:0021537 IMP telencephalon development
GO:0021846 IMP cell proliferation in forebrain
GO:0030900 IMP forebrain development
GO:0032355 IEA response to estradiol
GO:0032403 IEA protein complex binding
GO:0035259 IEA glucocorticoid receptor binding
GO:0042593 IMP glucose homeostasis
GO:0042698 IEA ovulation cycle
GO:0042826 IEA histone deacetylase binding
GO:0042974 IEA retinoic acid receptor binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045599 IMP negative regulation of fat cell differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046965 IEA retinoid X receptor binding
GO:0047485 IEA protein N-terminus binding
GO:0050872 IMP white fat cell differentiation
GO:0060206 IEA estrous cycle phase
GO:0060509 IGI Type I pneumocyte differentiation
GO:0072365 IEA regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000356219 NCOR2-201 protein_coding Homo_sapiens 0 4342
ENST00000404121 NCOR2-202 protein_coding Homo_sapiens 0 4342
ENST00000404621 NCOR2-002 protein_coding Homo_sapiens 0 3360
ENST00000405201 NCOR2-005 protein_coding Homo_sapiens 0 4342
ENST00000413172 NCOR2-018 protein_coding Homo_sapiens 0 593
ENST00000420698 NCOR2-004 protein_coding Homo_sapiens 0 1738
ENST00000429285 NCOR2-001 protein_coding Homo_sapiens 0 4246
ENST00000440187 NCOR2-013 protein_coding Homo_sapiens 0 333
ENST00000440337 NCOR2-015 protein_coding Homo_sapiens 0 359
ENST00000443451 NCOR2-022 retained_intron Homo_sapiens 0 603
ENST00000448008 NCOR2-019 protein_coding Homo_sapiens 0 516
ENST00000448614 NCOR2-009 protein_coding Homo_sapiens 0 289
ENST00000453428 NCOR2-012 protein_coding Homo_sapiens 0 298
ENST00000458234 NCOR2-003 protein_coding Homo_sapiens 0 2477
ENST00000461081 NCOR2-006 retained_intron Homo_sapiens 0 521
ENST00000464377 NCOR2-016 retained_intron Homo_sapiens 0 531
ENST00000474079 NCOR2-014 retained_intron Homo_sapiens 0 289
ENST00000494460 NCOR2-007 retained_intron Homo_sapiens 4e-37 158
ENST00000542927 NCOR2-024 protein_coding Homo_sapiens 0 955

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