C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: oligophrenin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031214 Ophn1 10090 - X:98554277-98891025 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033560 Ophn1-001 98554277-98890985 protein_coding
  ENSMUST00000113826 Ophn1-004 98558251-98890781 protein_coding
  ENSMUST00000125150 Ophn1-005 98712199-98891025 retained_intron
  ENSMUST00000140598 Ophn1-008 98873726-98890384 processed_transcript
  ENSMUST00000142267 Ophn1-002 98732392-98890985 protein_coding
  ENSMUST00000147529 Ophn1-009 98558257-98578489 protein_coding
  ENSMUST00000147805 Ophn1-006 98712427-98890985 retained_intron
  ENSMUST00000154920 Ophn1-010 98563569-98578435 processed_transcript
  ENSMUST00000156634 Ophn1-003 98887780-98890625 retained_intron
  ENSMUST00000156917 Ophn1-007 98801801-98890609 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033560ENSMUST00000113826ENSMUST00000125150ENSMUST00000142267ENSMUST00000147805ENSMUST00000156634ENSMUST00000156917
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033560 1.545±0.46 N/A 1.149±0.08 4.049±0.28 1.376±0.21 0.708±0.20 0.213±0.00 0.389±0.15 0.167±0.08 0.873±0.23 0.221±0.09 0.803±0.31 0.137±0.07 N/A
ENSMUST00000113826 2.585±0.75 N/A 2.695±0.04 3.923±0.83 1.422±0.15 0.761±0.17 0.713±0.14 0.359±0.11 0.328±0.16 0.578±0.05 0.652±0.17 3.198±1.44 0.521±0.21 3.671±0.42
ENSMUST00000125150 N/A 0.621±0.07 N/A N/A N/A N/A N/A N/A 0.064±0.01 N/A N/A 0.706±0.00 N/A N/A
ENSMUST00000142267 3.964±0.48 1.855±0.39 N/A N/A 4.543±0.79 4.342±0.58 N/A 0.963±0.26 0.266±0.09 3.239±1.12 N/A 5.345±1.25 N/A N/A
ENSMUST00000147805 N/A N/A N/A N/A N/A N/A 0.434±0.00 N/A 0.060±0.00 N/A N/A 1.027±0.00 N/A N/A
ENSMUST00000156634 N/A N/A N/A N/A N/A N/A N/A N/A 0.096±0.02 N/A N/A N/A N/A N/A
ENSMUST00000156917 N/A 3.453±1.43 N/A N/A 5.572±0.44 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001SR CIL_0001SR_0003 CGP X:98149721-98891025
CIL_0001SQ CIL_0001SQ_0003 CGP X:98554277-98949017

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IDA actin binding
GO:0005100 IMP Rho GTPase activator activity
GO:0005515 IPI protein binding
GO:0005543 IEA phospholipid binding
GO:0005737 IDA cytoplasm
GO:0007165 IEA signal transduction
GO:0007399 IEA nervous system development
GO:0015629 IDA actin cytoskeleton
GO:0030036 IDA actin cytoskeleton organization
GO:0030054 IEA cell junction
GO:0030100 IMP regulation of endocytosis
GO:0030425 IDA dendrite
GO:0032321 IMP positive regulation of Rho GTPase activity
GO:0035255 IEA ionotropic glutamate receptor binding
GO:0043195 IDA terminal bouton
GO:0043197 IDA dendritic spine
GO:0048488 IGI synaptic vesicle endocytosis
GO:0051966 IMP regulation of synaptic transmission, glutamatergic
GO:1901799 IDA negative regulation of proteasomal protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035420 ophn1 oligophrenin 1 protein_coding Danio_rerio
ENSG00000079482 OPHN1 oligophrenin 1 protein_coding Homo_sapiens

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