C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transducin-like enhancer of split 3, homolog of Drosophila E(spl)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032280 Tle3 10090 + 9:61372366-61418497 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034820 Tle3-002 61372858-61418487 protein_coding
  ENSMUST00000159050 Tle3-007 61373438-61416716 protein_coding
  ENSMUST00000159140 Tle3-012 61402461-61417835 retained_intron
  ENSMUST00000159386 Tle3-008 61372383-61417905 protein_coding
  ENSMUST00000159630 Tle3-010 61373535-61418080 protein_coding
  ENSMUST00000160541 Tle3-015 61373482-61401892 protein_coding
  ENSMUST00000160724 Tle3-004 61373416-61407439 protein_coding
  ENSMUST00000160882 Tle3-003 61373385-61417837 protein_coding
  ENSMUST00000161194 Tle3-016 61374329-61394637 protein_coding
  ENSMUST00000161207 Tle3-006 61373514-61416976 protein_coding
  ENSMUST00000161689 Tle3-011 61373672-61416976 protein_coding
  ENSMUST00000161993 Tle3-014 61373381-61409365 protein_coding
  ENSMUST00000162127 Tle3-009 61375529-61416976 protein_coding
  ENSMUST00000162281 Tle3-018 61409937-61418419 processed_transcript
  ENSMUST00000162583 Tle3-005 61373219-61418486 protein_coding
  ENSMUST00000162962 Tle3-017 61401859-61410134 processed_transcript
  ENSMUST00000162973 Tle3-001 61373417-61418490 protein_coding
  ENSMUST00000178113 Tle3-201 61372366-61418497 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034820ENSMUST00000159050ENSMUST00000159140ENSMUST00000159386ENSMUST00000159630ENSMUST00000160541ENSMUST00000160724ENSMUST00000160882ENSMUST00000161207ENSMUST00000161689ENSMUST00000162127ENSMUST00000162973ENSMUST00000178113
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034820 3.216±0.00 10.017±0.00 N/A N/A 2.674±0.00 N/A N/A 2.205±0.00 0.666±0.11 2.638±0.00 0.418±0.03 N/A 7.692±2.19 N/A
ENSMUST00000159050 8.989±0.96 19.675±5.10 N/A 10.402±1.54 12.460±3.10 8.112±2.21 1.417±0.12 5.098±1.10 1.393±0.33 7.019±2.17 0.577±0.00 12.744±1.57 N/A 25.419±2.26
ENSMUST00000159140 1.706±0.12 N/A N/A 2.016±0.00 1.105±0.41 N/A 0.288±0.00 N/A 0.318±0.00 N/A 0.145±0.05 N/A N/A N/A
ENSMUST00000159386 4.162±0.38 N/A N/A N/A 5.177±0.00 3.497±0.00 0.729±0.00 N/A N/A N/A 0.415±0.05 4.186±1.04 15.188±0.00 1.512±0.00
ENSMUST00000159630 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.273±0.00 N/A N/A N/A
ENSMUST00000160541 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 171.181±0.00 N/A
ENSMUST00000160724 N/A N/A N/A 16.383±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 74.320±0.00 71.931±0.00
ENSMUST00000160882 4.259±0.18 N/A N/A 2.490±0.00 4.914±1.04 N/A 1.269±0.38 N/A 0.878±0.03 3.011±0.00 0.457±0.06 5.449±2.04 15.324±1.98 N/A
ENSMUST00000161207 10.627±2.29 22.764±3.12 7.735±0.00 16.345±0.23 17.576±4.50 15.721±0.82 2.371±1.04 9.377±1.25 2.221±0.72 10.034±2.96 0.927±0.00 17.911±1.84 11.558±1.49 34.741±3.18
ENSMUST00000161689 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.047±0.95
ENSMUST00000162127 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.138±0.00
ENSMUST00000162973 N/A N/A 3.939±0.00 N/A N/A N/A N/A 3.995±0.00 0.529±0.00 N/A 0.335±0.13 7.606±0.00 11.478±0.00 N/A
ENSMUST00000178113 5.266±1.16 11.668±3.72 4.940±1.31 8.319±2.78 8.537±4.06 6.326±2.02 N/A 2.433±0.15 0.921±0.35 4.059±0.98 N/A 7.493±2.01 7.137±0.29 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008V4 CIL_0008V4_0002 VISTA 9:61070058-61671069
CIL_0009BU CIL_0009BU_0002 VISTA 9:61300844-61903666

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007275 IEA multicellular organismal development
GO:0007283 IEA spermatogenesis
GO:0016055 IEA Wnt signaling pathway
GO:0030154 IEA cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002787 gro2 groucho 2 protein_coding Danio_rerio
ENSDARG00000069006 gro1 groucho 1 protein_coding Danio_rerio
ENSG00000140332 TLE3 transducin-like enhancer of split 3 protein_coding Homo_sapiens

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