C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CCR4-NOT transcription complex, subunit 6-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034724 Cnot6l 10090 - 5:96070333-96164171 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000036646 Cnot6l-002 96075589-96161755 nonsense_mediated_decay
  ENSMUST00000113005 Cnot6l-201 96075737-96161755 protein_coding
  ENSMUST00000122003 Cnot6l-003 96076801-96161547 protein_coding
  ENSMUST00000129646 Cnot6l-007 96106299-96161742 protein_coding
  ENSMUST00000137066 Cnot6l-009 96105610-96131060 retained_intron
  ENSMUST00000137207 Cnot6l-006 96131097-96164171 protein_coding
  ENSMUST00000141383 Cnot6l-008 96131061-96161871 protein_coding
  ENSMUST00000152490 Cnot6l-005 96075576-96086933 retained_intron
  ENSMUST00000154500 Cnot6l-004 96131208-96161763 protein_coding
  ENSMUST00000155901 Cnot6l-001 96070333-96161990 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000036646ENSMUST00000113005ENSMUST00000122003ENSMUST00000152490ENSMUST00000155901
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000036646 N/A 1.806±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000113005 2.876±0.89 2.064±0.74 N/A N/A 3.407±0.71 2.438±0.78 1.609±0.17 2.670±0.60 1.683±0.38 3.654±0.82 N/A 2.353±0.87 4.780±1.21 1.808±0.80
ENSMUST00000122003 N/A N/A N/A N/A 3.088±1.07 N/A N/A N/A N/A N/A N/A 1.555±0.00 7.802±0.00 1.995±0.00
ENSMUST00000152490 N/A 3.660±0.19 N/A N/A 2.258±0.73 3.535±1.66 N/A N/A 1.278±0.00 N/A N/A 4.550±0.81 N/A 0.626±0.00
ENSMUST00000155901 1.589±0.62 N/A 4.062±0.44 3.053±0.95 1.826±1.02 1.621±0.49 1.506±0.47 2.654±0.84 2.040±0.70 3.002±0.51 1.406±0.39 2.512±1.11 1.700±0.82 0.471±0.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00069Y CIL_00069Y_0002 CGP 5:95956928-96164171
CIL_0007HW CIL_0007HW_0003 CGP 5:96070333-96266727

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000288 IMP nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0004535 IMP poly(A)-specific ribonuclease activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006397 IEA mRNA processing
GO:0006417 IEA regulation of translation
GO:0008284 IMP positive regulation of cell proliferation
GO:0010606 ISS positive regulation of cytoplasmic mRNA processing body assembly
GO:0030014 ISS CCR4-NOT complex
GO:0031047 IEA gene silencing by RNA
GO:0046872 IEA metal ion binding
GO:0061157 IMP mRNA destabilization
GO:0090503 IMP RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054597 cnot6l CCR4-NOT transcription complex, subunit 6-like protein_coding Danio_rerio
ENSG00000138767 CNOT6L CCR4-NOT transcription complex, subunit 6-like protein_coding Homo_sapiens

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