C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: suppressor of cancer cell invasion
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035236 Scai 10090 - 2:39066214-39190730 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038874 Scai-001 39066214-39190730 protein_coding
  ENSMUST00000131225 Scai-005 39106709-39108763 retained_intron
  ENSMUST00000142872 Scai-004 39132979-39190728 protein_coding
  ENSMUST00000147433 Scai-002 39080044-39190730 nonsense_mediated_decay
  ENSMUST00000157038 Scai-003 39103482-39190730 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038874ENSMUST00000142872ENSMUST00000147433ENSMUST00000157038
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038874 1.142±0.33 0.629±0.21 0.903±0.07 1.922±0.43 0.739±0.22 0.438±0.11 0.260±0.16 0.383±0.20 0.305±0.25 0.201±0.02 0.246±0.09 1.109±0.72 0.203±0.09 0.979±0.00
ENSMUST00000142872 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.413±0.00 N/A N/A
ENSMUST00000147433 N/A 0.253±0.00 N/A N/A N/A N/A 0.288±0.00 0.456±0.09 0.244±0.08 0.598±0.05 N/A 0.462±0.00 1.153±0.00 1.510±0.04
ENSMUST00000157038 N/A 0.257±0.00 N/A N/A N/A 0.307±0.00 N/A N/A N/A N/A N/A 1.000±0.49 0.302±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00075F CIL_00075F_0002 CGP 2:39016261-39190730
CIL_00075C CIL_00075C_0002 CGP 2:39066214-39226451

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0016021 IEA integral component of membrane
GO:0030336 IGI negative regulation of cell migration
GO:0035024 IDA negative regulation of Rho protein signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060865 scai suppressor of cancer cell invasion protein_coding Danio_rerio
ENSG00000173611 SCAI suppressor of cancer cell invasion protein_coding Homo_sapiens

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