C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: suppressor of cancer cell invasion
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173611 SCAI 9606 - 9:124942608-125143506 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336505 SCAI-001 124942608-125143496 protein_coding
  ENST00000373549 SCAI-003 124952788-125143496 protein_coding
  ENST00000467917 SCAI-006 124952869-124999923 nonsense_mediated_decay
  ENST00000468569 SCAI-005 125142254-125143506 retained_intron
  ENST00000477186 SCAI-004 124952788-125143487 nonsense_mediated_decay
  ENST00000487795 SCAI-002 124999911-125003690 processed_transcript
  ENST00000494102 SCAI-007 124971258-124976186 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartLiverLungMuscleOvaryENST00000336505ENST00000373549
Transcript ID Adipose Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary
ENST00000336505 0.297±0.00 N/A 2.811±0.17 N/A 0.218±0.00 0.335±0.11 1.182±0.00 0.939±0.67 0.627±0.00 0.630±0.24
ENST00000373549 N/A 1.366±0.00 8.250±0.00 2.476±0.00 N/A 0.653±0.00 N/A 3.128±0.00 0.723±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002C7 CIL_0002C7_0002 CGP 9:124862130-124948492
CIL_00075F CIL_00075F_0001 CGP 9:124878357-125143506
CIL_00075C CIL_00075C_0001 CGP 9:124942608-125189939

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003714 IMP:IEA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0016021 IEA integral component of membrane
GO:0030336 IMP negative regulation of cell migration
GO:0035024 ISS negative regulation of Rho protein signal transduction
GO:2001141 IEA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060865 scai suppressor of cancer cell invasion protein_coding Danio_rerio
ENSMUSG00000035236 Scai suppressor of cancer cell invasion protein_coding Mus_musculus

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