C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: retinoid X receptor beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039656 Rxrb 10090 + 17:34031812-34038393 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000044858 Rxrb-001 34031812-34038393 protein_coding
  ENSMUST00000116612 Rxrb-003 34032401-34038393 protein_coding
  ENSMUST00000173354 Rxrb-002 34032375-34037815 protein_coding
  ENSMUST00000173554 Rxrb-004 34032196-34034202 protein_coding
  ENSMUST00000174033 Rxrb-008 34036367-34037307 retained_intron
  ENSMUST00000174130 Rxrb-005 34033908-34036373 retained_intron
  ENSMUST00000174299 Rxrb-010 34032183-34037700 protein_coding
  ENSMUST00000174578 Rxrb-009 34036463-34037534 retained_intron
  ENSMUST00000174645 Rxrb-007 34036323-34037274 retained_intron
  ENSMUST00000174740 Rxrb-006 34033552-34036010 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044858ENSMUST00000116612ENSMUST00000173354ENSMUST00000173554ENSMUST00000174130ENSMUST00000174299
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044858 7.935±1.84 43.863±8.24 11.450±0.68 33.191±13.17 21.181±8.06 24.545±2.97 5.086±2.13 10.363±1.60 6.675±1.44 20.515±6.47 4.825±0.96 27.206±7.56 4.283±2.25 4.764±1.22
ENSMUST00000116612 7.596±0.76 N/A 5.630±1.12 6.738±3.76 5.488±2.92 N/A 6.189±0.38 6.600±0.85 4.757±1.20 N/A 8.697±1.10 9.731±1.97 5.985±2.74 2.591±0.81
ENSMUST00000173354 4.971±0.94 N/A N/A N/A 6.213±1.36 N/A N/A 4.757±0.83 2.992±1.09 N/A 3.613±1.01 8.127±0.00 N/A N/A
ENSMUST00000173554 N/A 9.541±0.00 N/A 23.426±0.00 13.951±1.18 N/A N/A N/A N/A N/A N/A 25.408±0.00 11.836±0.51 1.133±0.00
ENSMUST00000174130 N/A N/A N/A 19.327±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 7.437±0.00 4.931±0.00
ENSMUST00000174299 6.104±0.14 N/A 5.636±0.82 11.489±3.94 4.987±0.00 10.909±0.87 3.097±0.27 N/A 3.745±0.48 8.260±0.23 3.915±0.54 8.667±3.28 8.143±2.15 2.105±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001228 IEA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001701 IGI in utero embryonic development
GO:0001893 IGI maternal placenta development
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004886 IDA 9-cis retinoic acid receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0042803 IDA protein homodimerization activity
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IGI sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048384 IDA retinoic acid receptor signaling pathway
GO:0055012 IGI ventricular cardiac muscle cell differentiation
GO:0060038 IGI cardiac muscle cell proliferation
GO:0071300 IDA cellular response to retinoic acid

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002006 rxrbb retinoid x receptor, beta b protein_coding Danio_rerio
ENSDARG00000078954 rxrba retinoid x receptor, beta a protein_coding Danio_rerio
ENSG00000204231 RXRB retinoid X receptor, beta protein_coding Homo_sapiens

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