C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tetratricopeptide repeat domain 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040785 Ttc3 10090 + 16:94370618-94469222 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000117648 Ttc3-001 94370618-94469222 protein_coding
  ENSMUST00000119131 Ttc3-011 94370798-94396626 protein_coding
  ENSMUST00000122895 Ttc3-007 94370781-94442679 protein_coding
  ENSMUST00000127667 Ttc3-020 94370797-94410840 protein_coding
  ENSMUST00000127911 Ttc3-018 94370767-94409710 processed_transcript
  ENSMUST00000129536 Ttc3-028 94466522-94468217 retained_intron
  ENSMUST00000130960 Ttc3-014 94370751-94416360 processed_transcript
  ENSMUST00000131429 Ttc3-027 94465161-94468885 retained_intron
  ENSMUST00000139513 Ttc3-015 94370751-94418621 nonsense_mediated_decay
  ENSMUST00000139607 Ttc3-026 94440093-94448745 retained_intron
  ENSMUST00000141176 Ttc3-025 94425148-94433154 protein_coding
  ENSMUST00000141192 Ttc3-030 94451126-94460077 nonsense_mediated_decay
  ENSMUST00000141856 Ttc3-012 94370751-94422296 protein_coding
  ENSMUST00000143145 Ttc3-004 94370757-94442679 nonsense_mediated_decay
  ENSMUST00000145432 Ttc3-010 94370750-94396382 nonsense_mediated_decay
  ENSMUST00000145883 Ttc3-023 94370823-94420280 protein_coding
  ENSMUST00000147046 Ttc3-009 94370796-94427865 protein_coding
  ENSMUST00000147352 Ttc3-002 94370739-94442667 protein_coding
  ENSMUST00000149753 Ttc3-024 94370743-94403807 retained_intron
  ENSMUST00000149885 Ttc3-021 94370797-94403343 protein_coding
  ENSMUST00000150097 Ttc3-019 94370780-94415958 protein_coding
  ENSMUST00000150346 Ttc3-006 94370743-94434345 protein_coding
  ENSMUST00000151192 Ttc3-022 94370798-94412109 processed_transcript
  ENSMUST00000151770 Ttc3-008 94370781-94442679 protein_coding
  ENSMUST00000152117 Ttc3-005 94370767-94442669 protein_coding
  ENSMUST00000153062 Ttc3-016 94370767-94390263 nonsense_mediated_decay
  ENSMUST00000153988 Ttc3-013 94370749-94418693 protein_coding
  ENSMUST00000154196 Ttc3-029 94457397-94467994 retained_intron
  ENSMUST00000154243 Ttc3-017 94370767-94387369 nonsense_mediated_decay
  ENSMUST00000155692 Ttc3-003 94370746-94442672 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000117648ENSMUST00000130960ENSMUST00000139513ENSMUST00000141176ENSMUST00000141192ENSMUST00000154196ENSMUST00000154243
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000117648 14.689±5.91 13.985±4.57 12.970±1.89 81.692±0.00 12.313±5.17 2.664±0.60 10.450±0.47 6.588±3.63 3.154±2.31 12.028±0.25 7.651±0.76 15.428±7.98 7.978±2.50 2.802±1.35
ENSMUST00000130960 N/A 42.691±2.37 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000139513 N/A 53.586±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000141176 N/A N/A N/A 378.265±0.00 N/A N/A N/A N/A N/A N/A N/A 87.940±0.00 35.046±0.00 16.324±0.00
ENSMUST00000141192 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 60.996±0.00 N/A N/A
ENSMUST00000154196 N/A N/A N/A 284.582±0.00 N/A N/A N/A N/A N/A N/A N/A 56.197±0.00 26.809±1.31 9.159±0.00
ENSMUST00000154243 N/A 37.262±7.76 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001CY CIL_0001CY_0003 CGP 16:94328420-94371015
CIL_0001CX CIL_0001CX_0003 CGP 16:94358763-94469222
CIL_0001D0 CIL_0001D0_0003 CGP 16:94370618-94526830

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005739 IEA mitochondrion
GO:0005773 IDA vacuole
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0008270 IEA zinc ion binding
GO:0010771 IDA negative regulation of cell morphogenesis involved in differentiation
GO:0016874 IEA ligase activity
GO:0045665 IDA negative regulation of neuron differentiation
GO:0070936 IEA protein K48-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086075 ttc3 tetratricopeptide repeat domain 3 protein_coding Danio_rerio
ENSG00000182670 TTC3 tetratricopeptide repeat domain 3 protein_coding Homo_sapiens

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