C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transformation related protein 53 binding protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000043909 Trp53bp1 10090 - 2:121193281-121271407 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000110647 Trp53bp1-002 121194838-121271341 protein_coding
  ENSMUST00000110648 Trp53bp1-001 121194838-121271407 protein_coding
  ENSMUST00000124031 Trp53bp1-011 121232100-121235821 processed_transcript
  ENSMUST00000124060 Trp53bp1-008 121269630-121271370 retained_intron
  ENSMUST00000124411 Trp53bp1-014 121208845-121221232 retained_intron
  ENSMUST00000124554 Trp53bp1-019 121208420-121221241 nonsense_mediated_decay
  ENSMUST00000129752 Trp53bp1-010 121236824-121252027 nonsense_mediated_decay
  ENSMUST00000131245 Trp53bp1-003 121216143-121271321 protein_coding
  ENSMUST00000131426 Trp53bp1-009 121258886-121270286 retained_intron
  ENSMUST00000132812 Trp53bp1-015 121205081-121208574 processed_transcript
  ENSMUST00000135890 Trp53bp1-006 121193281-121211975 processed_transcript
  ENSMUST00000136617 Trp53bp1-004 121256514-121271369 processed_transcript
  ENSMUST00000140285 Trp53bp1-005 121267312-121271361 retained_intron
  ENSMUST00000140582 Trp53bp1-013 121211308-121218436 processed_transcript
  ENSMUST00000142400 Trp53bp1-017 121228369-121235689 protein_coding
  ENSMUST00000147540 Trp53bp1-007 121198251-121236006 nonsense_mediated_decay
  ENSMUST00000147554 Trp53bp1-016 121199639-121204981 processed_transcript
  ENSMUST00000154426 Trp53bp1-018 121202693-121207762 nonsense_mediated_decay
  ENSMUST00000156493 Trp53bp1-012 121215889-121221379 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000110647ENSMUST00000110648ENSMUST00000131245ENSMUST00000135890ENSMUST00000140582ENSMUST00000147540
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000110647 N/A N/A N/A 7.078±0.00 1.692±0.00 N/A N/A N/A 2.485±0.00 N/A N/A 6.776±2.07 2.737±0.74 N/A
ENSMUST00000110648 5.348±2.41 3.806±0.43 7.189±1.01 22.948±2.97 3.562±1.09 3.520±0.94 1.773±0.22 2.100±0.31 3.494±2.71 3.999±1.08 1.914±0.42 6.083±1.48 4.373±0.98 4.912±0.59
ENSMUST00000131245 N/A N/A N/A 30.297±0.00 N/A N/A N/A N/A N/A N/A N/A 11.957±0.00 11.032±0.00 29.045±0.00
ENSMUST00000135890 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.537±2.27
ENSMUST00000140582 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 44.038±7.95 N/A N/A
ENSMUST00000147540 6.970±2.55 5.875±0.53 7.600±2.28 24.184±1.36 N/A 3.739±0.00 2.530±0.17 3.477±0.00 11.183±4.20 3.230±0.00 1.401±0.00 8.237±2.03 7.389±2.81 8.425±1.95

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005YH CIL_0005YH_0002 CGP 2:121158273-121198770
CIL_0005YA CIL_0005YA_0002 CGP 2:121170654-121271407
CIL_0005YB CIL_0005YB_0002 CGP 2:121193281-121310832

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000776 IDA kinetochore
GO:0000781 IEA chromosome, telomeric region
GO:0001102 IEA RNA polymerase II activating transcription factor binding
GO:0001104 IEA RNA polymerase II transcription cofactor activity
GO:0002039 IEA p53 binding
GO:0003684 IDA damaged DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005657 IDA replication fork
GO:0005737 IEA cytoplasm
GO:0006281 IDA DNA repair
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006974 ISO cellular response to DNA damage stimulus
GO:0008134 TAS transcription factor binding
GO:0035064 IEA methylated histone binding
GO:0042162 IDA telomeric DNA binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079000 TP53BP1 tumor protein p53 binding protein 1 protein_coding Danio_rerio
ENSG00000067369 TP53BP1 tumor protein p53 binding protein 1 protein_coding Homo_sapiens

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