C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor protein p53 binding protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000067369 TP53BP1 9606 - 15:43403061-43510728 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263801 TP53BP1-002 43407209-43510614 protein_coding
  ENST00000382039 TP53BP1-004 43407214-43493105 protein_coding
  ENST00000382044 TP53BP1-001 43403061-43493171 protein_coding
  ENST00000411772 TP53BP1-011 43407214-43456331 nonsense_mediated_decay
  ENST00000413546 TP53BP1-005 43432649-43493086 protein_coding
  ENST00000414758 TP53BP1-006 43447155-43456024 processed_transcript
  ENST00000417342 TP53BP1-008 43421090-43438407 nonsense_mediated_decay
  ENST00000434561 TP53BP1-009 43413269-43420374 nonsense_mediated_decay
  ENST00000434595 TP53BP1-010 43409010-43413286 protein_coding
  ENST00000450115 TP53BP1-014 43407216-43493127 protein_coding
  ENST00000467474 TP53BP1-013 43421672-43428116 protein_coding
  ENST00000476454 TP53BP1-003 43407214-43417216 retained_intron
  ENST00000477089 TP53BP1-012 43497438-43510728 processed_transcript
  ENST00000480860 TP53BP1-007 43441259-43456152 retained_intron
  ENST00000571145 TP53BP1-016 43415722-43421057 processed_transcript
  ENST00000572085 TP53BP1-015 43415222-43493156 retained_intron
  ENST00000605155 TP53BP1-018 43446533-43456178 processed_transcript

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000382039ENST00000382044ENST00000411772ENST00000450115ENST00000572085
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000382039 N/A N/A N/A N/A N/A N/A 1.351±0.00 0.717±0.00 N/A N/A N/A N/A N/A N/A
ENST00000382044 2.370±0.00 1.014±0.00 1.376±0.00 4.060±0.64 1.412±0.07 2.019±0.14 3.258±0.00 5.152±0.00 1.875±1.35 2.266±0.16 2.526±0.00 5.831±2.71 1.543±0.69 7.996±1.22
ENST00000411772 N/A N/A N/A N/A N/A 3.136±0.00 N/A 4.948±0.00 N/A 3.514±0.00 N/A 5.533±0.98 2.604±0.84 8.633±0.00
ENST00000450115 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.446±0.00 N/A
ENST00000572085 N/A N/A N/A N/A 2.309±0.00 N/A N/A N/A N/A 2.819±0.00 0.559±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005YH CIL_0005YH_0001 CGP 15:43358172-43409771
CIL_0005YA CIL_0005YA_0001 CGP 15:43369221-43510728
CIL_0005YB CIL_0005YB_0001 CGP 15:43403061-43531620

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000724 TAS double-strand break repair via homologous recombination
GO:0000776 IEA kinetochore
GO:0000781 IDA chromosome, telomeric region
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001104 IMP RNA polymerase II transcription cofactor activity
GO:0002039 IPI p53 binding
GO:0003684 IEA damaged DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005657 IEA replication fork
GO:0005737 IDA cytoplasm
GO:0006281 TAS DNA repair
GO:0006302 TAS double-strand break repair
GO:0006366 IMP transcription from RNA polymerase II promoter
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0035064 IDA methylated histone binding
GO:0042162 IEA telomeric DNA binding
GO:0043565 IEA sequence-specific DNA binding
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0051091 IC positive regulation of sequence-specific DNA binding transcription factor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079000 TP53BP1 tumor protein p53 binding protein 1 protein_coding Danio_rerio
ENSMUSG00000043909 Trp53bp1 transformation related protein 53 binding protein 1 protein_coding Mus_musculus

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