C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SRY (sex determining region Y)-box 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000051910 Sox6 10090 - 7:115471344-116038744 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000072804 Sox6-201 115471344-115995086 protein_coding
  ENSMUST00000106612 Sox6-202 115471344-116031047 protein_coding
  ENSMUST00000166207 Sox6-203 115476658-115846105 protein_coding
  ENSMUST00000166877 Sox6-204 115471344-116038744 protein_coding
  ENSMUST00000169129 Sox6-205 115474475-115824707 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonLiverLungOvaryPlacentaTestisENSMUST00000072804ENSMUST00000106612ENSMUST00000166207ENSMUST00000166877ENSMUST00000169129
Transcript ID Adipose Adrenal Brain Breast Colon Liver Lung Ovary Placenta Testis
ENSMUST00000072804 N/A N/A 0.865±0.00 N/A 0.238±0.08 1.960±0.00 0.143±0.00 0.319±0.13 0.168±0.00 N/A
ENSMUST00000106612 N/A N/A 0.557±0.00 0.188±0.00 N/A 0.735±0.32 0.077±0.00 0.355±0.00 N/A N/A
ENSMUST00000166207 N/A N/A 2.003±0.00 N/A N/A N/A N/A 0.368±0.25 0.240±0.00 16.894±16.22
ENSMUST00000166877 0.220±0.00 0.139±0.03 4.308±0.00 N/A 0.208±0.00 5.011±0.00 0.103±0.00 0.348±0.03 0.186±0.13 1.958±0.41
ENSMUST00000169129 N/A 0.291±0.03 N/A N/A N/A 0.338±0.00 N/A 0.123±0.00 0.073±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003ZR CIL_0003ZR_0002 CGP 7:114743694-116038744
CIL_0007MN CIL_0007MN_0003 UCNEbase 7:114963422-116027485
CIL_0007RU CIL_0007RU_0002 VISTA 7:115295838-115899194
CIL_0008U3 CIL_0008U3_0002 VISTA 7:115344905-115946551
CIL_0008HV CIL_0008HV_0002 VISTA 7:115445167-116046401
CIL_0007UO CIL_0007UO_0002 VISTA 7:115449542-116050857

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000902 IMP cell morphogenesis
GO:0001701 IMP in utero embryonic development
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0005667 IC transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0009791 IMP post-embryonic development
GO:0010468 IMP regulation of gene expression
GO:0016458 IMP gene silencing
GO:0021778 IMP oligodendrocyte cell fate specification
GO:0030097 IMP hemopoiesis
GO:0030218 IMP erythrocyte differentiation
GO:0032332 IDA positive regulation of chondrocyte differentiation
GO:0042692 IDA muscle cell differentiation
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045165 IGI cell fate commitment
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0048708 IEA astrocyte differentiation
GO:0048709 IMP oligodendrocyte differentiation
GO:0048821 IMP erythrocyte development
GO:0051216 IGI cartilage development
GO:0055007 IDA cardiac muscle cell differentiation
GO:0061036 IEA positive regulation of cartilage development
GO:0071560 IEA cellular response to transforming growth factor beta stimulus
GO:2000741 IEA positive regulation of mesenchymal stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015536 sox6 SRY-box containing gene 6 protein_coding Danio_rerio
ENSG00000110693 SOX6 SRY (sex determining region Y)-box 6 protein_coding Homo_sapiens

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