C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: actinin alpha 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000054808 Actn4 10090 - 7:28893248-28962340 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000068045 Actn4-001 28893248-28962340 protein_coding
  ENSMUST00000127210 Actn4-005 28898620-28962223 protein_coding
  ENSMUST00000129338 Actn4-008 28894232-28894852 retained_intron
  ENSMUST00000140622 Actn4-004 28907014-28919221 protein_coding
  ENSMUST00000143584 Actn4-007 28895642-28897031 retained_intron
  ENSMUST00000144909 Actn4-002 28893653-28907385 processed_transcript
  ENSMUST00000148196 Actn4-003 28913378-28949759 protein_coding
  ENSMUST00000150493 Actn4-006 28901915-28907686 processed_transcript

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000068045ENSMUST00000127210ENSMUST00000129338ENSMUST00000140622ENSMUST00000144909ENSMUST00000150493
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000068045 74.476±23.57 44.699±4.10 76.328±0.15 N/A 45.608±16.76 154.074±11.89 19.410±2.60 87.534±5.89 35.491±5.22 80.154±1.61 6.594±1.41 61.389±27.79 79.198±31.77 4.708±0.44
ENSMUST00000127210 N/A N/A N/A 22.577±16.28 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000129338 N/A N/A N/A N/A 64.425±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000140622 N/A N/A N/A N/A 59.825±0.00 N/A N/A N/A N/A N/A N/A 56.545±1.79 81.021±0.00 N/A
ENSMUST00000144909 56.973±6.39 29.315±6.28 44.521±1.67 19.238±5.23 42.039±11.00 129.177±22.20 16.655±0.33 45.969±12.11 22.607±6.74 38.078±0.95 3.708±0.99 42.666±16.59 70.122±42.71 12.776±3.81
ENSMUST00000150493 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 116.071±0.00 230.326±89.32 10.976±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0001725 IDA stress fiber
GO:0001882 IEA nucleoside binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005911 IDA cell-cell junction
GO:0005925 IEA focal adhesion
GO:0015031 IEA protein transport
GO:0030018 IDA Z disc
GO:0030529 ISS ribonucleoprotein complex
GO:0030863 IDA cortical cytoskeleton
GO:0031143 IDA pseudopodium
GO:0032403 IEA protein complex binding
GO:0042803 TAS protein homodimerization activity
GO:0042981 IEA regulation of apoptotic process
GO:0043005 IEA neuron projection
GO:0043234 IEA protein complex
GO:0044822 IEA poly(A) RNA binding
GO:0047485 IEA protein N-terminus binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048549 IMP positive regulation of pinocytosis
GO:0051015 IDA actin filament binding
GO:0051017 IDA actin filament bundle assembly
GO:0051271 IDA negative regulation of cellular component movement
GO:0051272 IDA positive regulation of cellular component movement
GO:0070062 IEA extracellular vesicular exosome
GO:0070830 IEA:IMP tight junction assembly
GO:1902396 IEA:IMP protein localization to tight junction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025364 ACTN4 (1 of 3) actinin, alpha 4 protein_coding Danio_rerio
ENSDARG00000089776 ACTN4 (2 of 3) actinin, alpha 4 protein_coding Danio_rerio
ENSG00000130402 ACTN4 actinin, alpha 4 protein_coding Homo_sapiens

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