C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DENN/MADD domain containing 1B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000056268 Dennd1b 10090 + 1:138963436-139176043 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000070283 Dennd1b-002 138963436-139063719 protein_coding
  ENSMUST00000094505 Dennd1b-001 138967721-139171912 protein_coding
  ENSMUST00000133941 Dennd1b-006 138963760-139081260 nonsense_mediated_decay
  ENSMUST00000137127 Dennd1b-007 139093157-139136315 processed_transcript
  ENSMUST00000138872 Dennd1b-004 139110384-139134172 retained_intron
  ENSMUST00000145931 Dennd1b-003 138963708-138966441 retained_intron
  ENSMUST00000146369 Dennd1b-005 139126075-139144000 processed_transcript
  ENSMUST00000168527 Dennd1b-201 138963709-139176043 protein_coding
  ENSMUST00000188420 Dennd1b-008 139085924-139093267 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000094505ENSMUST00000133941ENSMUST00000146369ENSMUST00000168527
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000094505 0.770±0.20 1.160±0.36 N/A 0.865±0.00 2.187±0.49 2.157±0.55 1.279±0.32 0.762±0.21 0.370±0.09 1.054±0.22 N/A 4.189±0.87 N/A 1.102±0.30
ENSMUST00000133941 N/A 2.147±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000146369 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 43.632±0.00
ENSMUST00000168527 0.951±0.04 0.688±0.22 0.750±0.14 1.801±1.15 1.223±0.43 1.222±0.26 0.946±0.37 0.472±0.32 0.697±0.36 1.247±0.20 0.817±0.31 0.880±0.19 1.248±0.85 0.604±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007N3 CIL_0007N3_0002 UCNEbase 1:138385353-139100523
CIL_0005VR CIL_0005VR_0002 CGP 1:138851979-139176043

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005575 ND cellular_component
GO:0015031 IEA protein transport
GO:0017112 ISS Rab guanyl-nucleotide exchange factor activity
GO:0031410 IEA cytoplasmic vesicle
GO:0032851 ISS positive regulation of Rab GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029374 dennd1b DENN/MADD domain containing 1B protein_coding Danio_rerio
ENSDARG00000090356 DENND1B (2 of 2) DENN/MADD domain containing 1B protein_coding Danio_rerio
ENSG00000213047 DENND1B DENN/MADD domain containing 1B protein_coding Homo_sapiens

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