C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sodium channel, voltage-gated, type III, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000057182 Scn3a 10090 - 2:65457118-65567627 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000066432 Scn3a-201 65457118-65567492 protein_coding
  ENSMUST00000100069 Scn3a-001 65458263-65567627 protein_coding
  ENSMUST00000126837 Scn3a-002 65524748-65529404 protein_coding
  ENSMUST00000155838 Scn3a-003 65493125-65498599 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066432ENSMUST00000100069ENSMUST00000126837ENSMUST00000155838
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066432 N/A N/A 0.011±0.00 N/A N/A N/A N/A 0.051±0.00 0.019±0.00 N/A 0.057±0.00 N/A N/A N/A
ENSMUST00000100069 0.051±0.02 0.409±0.21 0.068±0.01 6.049±1.67 0.130±0.06 0.503±0.13 0.280±0.04 0.072±0.02 0.047±0.03 6.684±1.96 0.074±0.03 0.400±0.13 0.015±0.01 0.078±0.04
ENSMUST00000126837 N/A N/A N/A N/A 0.741±0.00 N/A N/A N/A N/A N/A 0.477±0.00 N/A N/A N/A
ENSMUST00000155838 N/A N/A N/A N/A N/A N/A N/A N/A 0.039±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006CP CIL_0006CP_0002 CGP 2:65316430-65567627
CIL_0006CO CIL_0006CO_0002 CGP 2:65457118-65767447

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0005248 IBA voltage-gated sodium channel activity
GO:0005737 IDA cytoplasm
GO:0005886 IBA plasma membrane
GO:0016020 IDA membrane
GO:0019228 IBA neuronal action potential
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IBA sodium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010783 scn1a sodium channel, voltage-gated, type I, alpha protein_coding Danio_rerio
ENSDARG00000062744 scn1lab sodium channel, voltage-gated, type I like, alpha b protein_coding Danio_rerio
ENSG00000153253 SCN3A sodium channel, voltage-gated, type III, alpha subunit protein_coding Homo_sapiens

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