C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: breast carcinoma amplified sequence 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000059439 Bcas3 10090 + 11:85353167-85826058 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000074875 Bcas3-201 85353212-85825350 protein_coding
  ENSMUST00000092821 Bcas3-202 85353212-85825350 protein_coding
  ENSMUST00000092822 Bcas3-006 85509638-85826058 protein_coding
  ENSMUST00000108056 Bcas3-003 85353167-85510991 protein_coding
  ENSMUST00000108061 Bcas3-001 85353167-85826058 protein_coding
  ENSMUST00000108062 Bcas3-002 85353167-85826058 protein_coding
  ENSMUST00000130343 Bcas3-010 85640704-85826055 processed_transcript
  ENSMUST00000133194 Bcas3-011 85581042-85603044 processed_transcript
  ENSMUST00000138423 Bcas3-014 85353185-85371163 protein_coding
  ENSMUST00000140215 Bcas3-013 85492568-85495914 processed_transcript
  ENSMUST00000140562 Bcas3-009 85821966-85825307 processed_transcript
  ENSMUST00000142596 Bcas3-005 85509627-85826058 protein_coding
  ENSMUST00000144276 Bcas3-012 85470752-85496993 protein_coding
  ENSMUST00000145281 Bcas3-008 85821413-85825646 processed_transcript
  ENSMUST00000149662 Bcas3-007 85801821-85825390 protein_coding
  ENSMUST00000154396 Bcas3-004 85466159-85826058 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000074875ENSMUST00000092821ENSMUST00000092822ENSMUST00000108061ENSMUST00000108062ENSMUST00000130343ENSMUST00000145281ENSMUST00000154396
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000074875 N/A N/A N/A 4.037±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000092821 N/A N/A N/A 3.513±2.40 1.556±0.00 N/A N/A N/A 1.829±0.75 N/A N/A 4.357±1.40 3.057±1.05 2.187±0.37
ENSMUST00000092822 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.259±0.00 3.803±0.00 N/A N/A
ENSMUST00000108061 N/A N/A N/A N/A N/A 0.713±0.00 1.064±0.00 N/A N/A N/A 1.278±0.29 N/A N/A 1.156±0.15
ENSMUST00000108062 3.073±0.53 1.848±0.25 1.996±0.33 2.578±0.56 2.616±0.60 2.722±0.81 2.354±0.81 4.257±0.15 1.279±0.47 5.116±0.68 1.899±0.65 3.382±1.02 0.915±0.11 1.263±0.36
ENSMUST00000130343 N/A N/A 5.357±0.11 N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.497±0.38 N/A
ENSMUST00000145281 N/A 9.728±0.34 N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.041±0.00 6.426±0.19 N/A
ENSMUST00000154396 6.195±0.32 10.131±2.19 3.258±0.38 4.737±0.80 5.999±1.01 4.053±0.79 2.365±0.54 7.252±0.59 2.746±0.72 5.708±0.25 2.446±0.37 6.533±1.84 1.977±0.78 3.421±0.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000569 CIL_000569_0003 CGP 11:85311244-85826058
CIL_000703 CIL_000703_0002 CGP 11:85353167-85841948

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003682 ISS chromatin binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005881 IDA cytoplasmic microtubule
GO:0007030 IMP Golgi organization
GO:0008134 IEA transcription factor binding
GO:0010595 IDA positive regulation of endothelial cell migration
GO:0010698 IEA acetyltransferase activator activity
GO:0031023 IMP microtubule organizing center organization
GO:0031252 IDA cell leading edge
GO:0032864 IDA activation of Cdc42 GTPase activity
GO:0034259 IMP negative regulation of Rho GTPase activity
GO:0035035 IEA histone acetyltransferase binding
GO:0035148 IMP tube formation
GO:0035257 IEA nuclear hormone receptor binding
GO:0035327 ISS transcriptionally active chromatin
GO:0042393 IEA histone binding
GO:0043085 ISS positive regulation of catalytic activity
GO:0043089 IMP positive regulation of Cdc42 GTPase activity
GO:0045111 IDA intermediate filament cytoskeleton
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048487 ISS beta-tubulin binding
GO:0051491 IMP positive regulation of filopodium assembly
GO:0051895 IDA negative regulation of focal adhesion assembly
GO:0071391 ISS cellular response to estrogen stimulus
GO:0071944 IDA cell periphery
GO:0090316 IDA positive regulation of intracellular protein transport
GO:2000114 IMP regulation of establishment of cell polarity
GO:2000251 IDA positive regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090764 bcas3 breast carcinoma amplified sequence 3 protein_coding Danio_rerio
ENSG00000141376 BCAS3 breast carcinoma amplified sequence 3 protein_coding Homo_sapiens

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