C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kalirin, RhoGEF kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000061751 Kalrn 10090 - 16:33974258-34573532 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000076810 Kalrn-011 33975495-34456917 protein_coding
  ENSMUST00000089655 Kalrn-004 34152035-34514086 protein_coding
  ENSMUST00000114947 Kalrn-018 34177981-34262839 protein_coding
  ENSMUST00000114949 Kalrn-003 34153400-34263193 protein_coding
  ENSMUST00000114953 Kalrn-005 34152095-34262965 protein_coding
  ENSMUST00000114954 Kalrn-007 34152025-34263200 protein_coding
  ENSMUST00000114960 Kalrn-001 34152024-34514048 protein_coding
  ENSMUST00000114961 Kalrn-012 34049689-34573532 protein_coding
  ENSMUST00000114963 Kalrn-010 34013132-34163279 protein_coding
  ENSMUST00000114964 Kalrn-014 34013146-34096028 protein_coding
  ENSMUST00000114966 Kalrn-013 34013137-34097090 protein_coding
  ENSMUST00000114973 Kalrn-015 33974258-34095987 protein_coding
  ENSMUST00000124430 Kalrn-019 34244114-34252315 processed_transcript
  ENSMUST00000132002 Kalrn-016 33975163-33978726 retained_intron
  ENSMUST00000132569 Kalrn-008 34512749-34514115 processed_transcript
  ENSMUST00000137216 Kalrn-006 34218757-34262910 retained_intron
  ENSMUST00000142817 Kalrn-009 34013137-34392109 protein_coding
  ENSMUST00000151491 Kalrn-002 34153467-34513944 protein_coding
  ENSMUST00000156668 Kalrn-017 34357268-34361799 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000076810ENSMUST00000114949ENSMUST00000114954ENSMUST00000114961ENSMUST00000114963ENSMUST00000114964ENSMUST00000114973ENSMUST00000132002ENSMUST00000142817
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000076810 0.547±0.28 0.224±0.07 N/A N/A 0.248±0.12 0.669±0.00 N/A 0.350±0.07 N/A 0.508±0.13 N/A 1.077±0.18 N/A N/A
ENSMUST00000114949 N/A N/A N/A 50.882±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000114954 N/A N/A N/A 36.957±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000114961 N/A N/A N/A N/A 0.198±0.00 N/A N/A N/A N/A 0.537±0.00 N/A N/A N/A N/A
ENSMUST00000114963 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.436±0.95 N/A N/A
ENSMUST00000114964 N/A N/A 2.175±0.23 N/A 0.853±0.14 7.834±1.06 3.571±0.39 2.868±0.39 6.991±1.81 3.285±0.55 3.871±0.32 7.173±2.69 6.773±2.65 0.644±0.00
ENSMUST00000114973 N/A N/A N/A N/A N/A 1.733±0.26 N/A 0.536±0.03 N/A N/A N/A 1.324±0.13 0.313±0.00 N/A
ENSMUST00000132002 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.259±0.13
ENSMUST00000142817 0.652±0.00 0.476±0.00 1.003±0.00 N/A 0.193±0.01 0.700±0.07 0.554±0.17 0.415±0.10 N/A 0.939±0.20 0.517±0.06 1.395±0.50 0.632±0.06 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HE CIL_0008HE_0002 VISTA 16:33792411-34395018

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006468 IEA protein phosphorylation
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0046872 IEA metal ion binding
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063538 kalrnb kalirin, RhoGEF kinase b protein_coding Danio_rerio
ENSDARG00000078117 kalrna kalirin, RhoGEF kinase a protein_coding Danio_rerio
ENSG00000160145 KALRN kalirin, RhoGEF kinase protein_coding Homo_sapiens

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