C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate decarboxylase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000070880 Gad1 10090 + 2:70553072-70602014 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000094934 Gad1-001 70562042-70602014 protein_coding
  ENSMUST00000123330 Gad1-008 70563442-70585946 protein_coding
  ENSMUST00000130604 Gad1-002 70562042-70587136 nonsense_mediated_decay
  ENSMUST00000130618 Gad1-007 70553072-70567233 protein_coding
  ENSMUST00000130998 Gad1-004 70562899-70585121 protein_coding
  ENSMUST00000140478 Gad1-006 70566377-70602012 processed_transcript
  ENSMUST00000148210 Gad1-003 70562196-70584600 protein_coding
  ENSMUST00000155979 Gad1-005 70562163-70577130 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000094934ENSMUST00000123330ENSMUST00000130604ENSMUST00000130618ENSMUST00000130998ENSMUST00000140478ENSMUST00000148210ENSMUST00000155979
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000094934 N/A 0.157±0.02 N/A 19.780±1.33 0.076±0.02 0.135±0.00 N/A 0.063±0.03 N/A 0.065±0.00 N/A N/A 0.039±0.00 0.084±0.02
ENSMUST00000123330 N/A 0.106±0.00 N/A N/A 0.044±0.00 0.034±0.00 N/A N/A N/A 0.042±0.01 N/A 0.074±0.00 0.113±0.00 N/A
ENSMUST00000130604 N/A 0.169±0.02 N/A N/A N/A 0.080±0.00 N/A 0.182±0.00 N/A N/A N/A 0.080±0.00 N/A 0.052±0.01
ENSMUST00000130618 N/A 1.925±0.73 N/A N/A 0.291±0.15 0.231±0.07 N/A 0.595±0.24 N/A 0.127±0.00 N/A 0.344±0.00 0.236±0.04 0.454±0.20
ENSMUST00000130998 N/A N/A N/A N/A 0.029±0.00 N/A N/A 0.038±0.01 N/A 0.027±0.00 N/A N/A 0.039±0.01 0.038±0.00
ENSMUST00000140478 0.011±0.00 0.276±0.11 0.015±0.01 14.642±2.21 0.092±0.06 0.058±0.00 0.037±0.02 0.092±0.04 0.042±0.04 0.053±0.03 0.021±0.02 0.053±0.03 0.037±0.02 0.039±0.00
ENSMUST00000148210 N/A N/A N/A N/A N/A N/A N/A 0.105±0.01 N/A N/A N/A N/A 0.044±0.00 N/A
ENSMUST00000155979 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.103±0.09 N/A 0.012±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003SB CIL_0003SB_0003 CGP 2:70508819-70602014

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004351 IEA glutamate decarboxylase activity
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005938 IDA cell cortex
GO:0016831 IEA carboxy-lyase activity
GO:0019752 IEA carboxylic acid metabolic process
GO:0030170 IEA pyridoxal phosphate binding
GO:0030424 IDA axon
GO:0042136 IEA neurotransmitter biosynthetic process
GO:0043679 IDA axon terminus
GO:0044306 IDA neuron projection terminus
GO:0045202 IDA synapse
GO:0048786 IDA presynaptic active zone

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027419 gad1b glutamate decarboxylase 1b protein_coding Danio_rerio
ENSDARG00000093411 gad1a glutamate decarboxylase 1a protein_coding Danio_rerio
ENSG00000128683 GAD1 glutamate decarboxylase 1 (brain, 67kDa) protein_coding Homo_sapiens

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