C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sodium channel, voltage-gated, type II, alpha 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000075318 Scn2a1 10090 + 2:65620857-65767447 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028377 Scn2a1-001 65620857-65767447 protein_coding
  ENSMUST00000100067 Scn2a1-201 65670445-65767447 protein_coding
  ENSMUST00000138368 Scn2a1-003 65682280-65683866 processed_transcript
  ENSMUST00000144254 Scn2a1-002 65681048-65683872 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000028377ENSMUST00000100067ENSMUST00000138368ENSMUST00000144254
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000028377 0.134±0.00 N/A N/A 2.736±1.16 0.165±0.06 0.181±0.02 0.075±0.00 N/A 0.016±0.01 N/A 0.286±0.03 N/A 0.127±0.02
ENSMUST00000100067 0.074±0.00 0.079±0.02 0.403±0.00 7.564±4.52 0.126±0.04 N/A N/A 0.046±0.00 0.021±0.01 0.105±0.01 0.143±0.08 0.021±0.01 0.020±0.00
ENSMUST00000138368 N/A 0.312±0.00 N/A N/A N/A N/A N/A N/A 0.022±0.00 N/A N/A N/A N/A
ENSMUST00000144254 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.226±0.13 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006CO CIL_0006CO_0002 CGP 2:65457118-65767447
CIL_0006CJ CIL_0006CJ_0002 CGP 2:65620857-66031546

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 TAS voltage-gated sodium channel complex
GO:0005248 IDA voltage-gated sodium channel activity
GO:0006814 IDA sodium ion transport
GO:0007399 IMP nervous system development
GO:0008627 IMP intrinsic apoptotic signaling pathway in response to osmotic stress
GO:0014704 IDA intercalated disc
GO:0016020 IDA membrane
GO:0019228 IBA neuronal action potential
GO:0030315 IDA T-tubule
GO:0030424 IDA axon
GO:0033270 IDA paranode region of axon
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0051402 IMP neuron apoptotic process
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010783 scn1a sodium channel, voltage-gated, type I, alpha protein_coding Danio_rerio
ENSDARG00000062744 scn1lab sodium channel, voltage-gated, type I like, alpha b protein_coding Danio_rerio
ENSG00000136531 SCN2A sodium channel, voltage-gated, type II, alpha subunit protein_coding Homo_sapiens

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