C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fibroblast activation protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000000402 Fap-008 ENSMUSG00000000392 10090 - 2:62501184-62573851 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalColonLiverOvaryTestisENSMUST00000000402
Transcript ID Adrenal Colon Liver Ovary Testis
ENSMUST00000000402 0.133±0.04 0.213±0.00 0.043±0.00 0.406±0.19 0.025±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003S0 CIL_0003S0_0003 CGP 2:62474530-62574075
CIL_0005KX CIL_0005KX_0002 CGP 2:62500943-62646255

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004252 ISS serine-type endopeptidase activity
GO:0005886 ISS plasma membrane
GO:0006508 IEA:ISS proteolysis
GO:0008233 IDA peptidase activity
GO:0008236 ISS serine-type peptidase activity
GO:0008239 ISS dipeptidyl-peptidase activity
GO:0009986 IDA cell surface
GO:0010710 ISS regulation of collagen catabolic process
GO:0010716 ISS negative regulation of extracellular matrix disassembly
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030027 ISS lamellipodium
GO:0030054 IEA cell junction
GO:0042803 ISS protein homodimerization activity
GO:0043542 ISS endothelial cell migration
GO:0045177 IDA apical part of cell
GO:0045178 IDA basal part of cell
GO:0051603 ISS proteolysis involved in cellular protein catabolic process
GO:0060244 IDA negative regulation of cell proliferation involved in contact inhibition
GO:0071158 IDA positive regulation of cell cycle arrest
GO:0071438 ISS invadopodium membrane
GO:0071850 IDA mitotic cell cycle arrest
GO:0097325 IDA melanocyte proliferation
GO:1900119 IDA positive regulation of execution phase of apoptosis
GO:1902362 IDA melanocyte apoptotic process
GO:1903054 ISS negative regulation of extracellular matrix organization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000188790 FAP-001 protein_coding Homo_sapiens 0 2710
ENST00000422436 FAP-004 nonsense_mediated_decay Homo_sapiens 0 1099
ENST00000443424 FAP-015 protein_coding Homo_sapiens 0 2488
ENST00000447386 FAP-007 protein_coding Homo_sapiens 0 446
ENST00000461506 FAP-010 retained_intron Homo_sapiens 0 532
ENST00000462608 FAP-014 nonsense_mediated_decay Homo_sapiens 0 206
ENST00000465088 FAP-011 retained_intron Homo_sapiens 0 531
ENST00000465424 FAP-008 retained_intron Homo_sapiens 1.4013e-45 187
ENST00000480044 FAP-005 retained_intron Homo_sapiens 0 560
ENST00000480838 FAP-003 retained_intron Homo_sapiens 0 1164

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