C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, ionotropic, kainate 5 (gamma 2)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000003468 Grik5-201 ENSMUSG00000003378 10090 - 7:25009853-25072369 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003468
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003468 8.248±3.65 12.563±3.62 14.957±0.32 67.159±12.19 5.905±2.54 6.678±1.23 2.719±0.65 4.647±1.51 3.150±0.99 8.971±0.45 1.156±0.30 20.723±6.87 2.021±0.97 25.500±9.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003YN CIL_0003YN_0002 CGP 7:24978167-25072369
CIL_0003XZ CIL_0003XZ_0002 CGP 7:25009853-25083492

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005234 IBA extracellular-glutamate-gated ion channel activity
GO:0005515 IPI protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0006621 IEA protein retention in ER lumen
GO:0007165 IEA signal transduction
GO:0007268 IEA synaptic transmission
GO:0008066 IEA glutamate receptor activity
GO:0008328 IEA ionotropic glutamate receptor complex
GO:0014069 IEA postsynaptic density
GO:0015277 IGI kainate selective glutamate receptor activity
GO:0016020 IDA membrane
GO:0017124 IEA SH3 domain binding
GO:0030054 IEA cell junction
GO:0030165 IEA PDZ domain binding
GO:0030424 IEA axon
GO:0030425 IBA dendrite
GO:0031630 IMP regulation of synaptic vesicle fusion to presynaptic membrane
GO:0032983 IPI kainate selective glutamate receptor complex
GO:0034220 IEA ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IMP synaptic transmission, glutamatergic
GO:0042391 IGI regulation of membrane potential
GO:0042734 IDA presynaptic membrane
GO:0042802 IEA identical protein binding
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043113 IEA receptor clustering
GO:0043195 IEA terminal bouton
GO:0043204 IEA perikaryon
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0045211 IDA postsynaptic membrane
GO:0051649 IEA establishment of localization in cell
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0071333 IEA cellular response to glucose stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000114472 GRIK5 (2 of 2)-201 protein_coding Danio_rerio 0 1205
ENSDART00000134340 GRIK5 (2 of 2)-001 protein_coding Danio_rerio 0 462
ENSDART00000042083 gria4a-201 protein_coding Danio_rerio 0.0000000000003 82
ENSDART00000054599 gria4a-202 protein_coding Danio_rerio 0.0000000000003 82
ENST00000262895 GRIK5-002 protein_coding Homo_sapiens 0 4185
ENST00000301218 GRIK5-001 protein_coding Homo_sapiens 0 3683
ENST00000454993 GRIK5-003 retained_intron Homo_sapiens 0 2386
ENST00000593562 GRIK5-004 protein_coding Homo_sapiens 0 4623
ENST00000594528 GRIK5-005 nonsense_mediated_decay Homo_sapiens 0 2242
ENST00000602210 GRIK5-006 retained_intron Homo_sapiens 0 472

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