C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: CCCTC-binding factor (zinc finger protein)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264010 CTCF-001 ENSG00000102974 9606 + 16:67562407-67639183 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264010
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264010 10.008±0.00 11.076±0.00 1.609±0.00 6.291±3.21 6.010±2.73 7.691±4.10 4.460±3.73 5.577±3.62 3.431±0.13 6.045±1.70 5.370±4.28 10.583±9.00 7.619±0.55 7.662±2.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003LR CIL_0003LR_0002 CGP 16:67518418-67639183
CIL_0006LW CIL_0006LW_0002 CGP 16:67562407-67657569

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000775 IDA chromosome, centromeric region
GO:0000793 IDA condensed chromosome
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0006306 IEA DNA methylation
GO:0006349 IEA regulation of gene expression by genetic imprinting
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007059 IEA chromosome segregation
GO:0008270 TAS zinc ion binding
GO:0010216 IEA maintenance of DNA methylation
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IEA negative regulation of gene expression
GO:0016568 IEA chromatin modification
GO:0016584 IDA nucleosome positioning
GO:0031060 IEA regulation of histone methylation
GO:0035065 IEA regulation of histone acetylation
GO:0040029 IMP regulation of gene expression, epigenetic
GO:0040030 IMP regulation of molecular function, epigenetic
GO:0043035 IDA chromatin insulator sequence binding
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0070602 NAS regulation of centromeric sister chromatid cohesion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000005841 Ctcf-001 protein_coding Mus_musculus 0 4752
ENSMUST00000132679 Ctcf-002 processed_transcript Mus_musculus 0 1666
ENSMUST00000128510 Ctcf-003 processed_transcript Mus_musculus 0 630
ENSMUST00000156436 Ctcf-006 retained_intron Mus_musculus 0 505
ENSMUST00000137735 Ctcf-005 processed_transcript Mus_musculus 0 401

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