C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: large tumor suppressor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000022531 Lats2-001 ENSMUSG00000021959 10090 - 14:57689662-57746123 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022531
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022531 14.154±1.27 24.088±7.55 15.959±0.57 3.947±0.70 16.936±6.18 11.152±3.95 8.130±0.55 15.762±3.17 3.356±0.75 45.644±6.79 3.644±0.51 25.131±8.75 8.362±4.16 20.080±8.58

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003SP CIL_0003SP_0002 CGP 14:57549598-57665430
CIL_0003SQ CIL_0003SQ_0002 CGP 14:57581002-57758388
CIL_0003SR CIL_0003SR_0002 CGP 14:57642077-57804980

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IDA G1/S transition of mitotic cell cycle
GO:0000922 IDA spindle pole
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005524 ISS ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006468 IDA:ISS protein phosphorylation
GO:0007067 IEA mitotic nuclear division
GO:0009755 ISS hormone-mediated signaling pathway
GO:0030216 IGI keratinocyte differentiation
GO:0034613 IDA cellular protein localization
GO:0035329 IGI hippo signaling
GO:0035556 ISS intracellular signal transduction
GO:0045736 ISS negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0046620 IMP regulation of organ growth
GO:0046872 IEA metal ion binding
GO:0090090 IGI negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000382592 LATS2-001 protein_coding Homo_sapiens 0 1820

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