C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: metadherin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000022865 Mtdh-001 ENSMUSG00000022255 10090 + 15:34082719-34142386 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022865
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022865 8.528±3.11 9.434±5.35 18.656±1.48 11.695±0.50 14.475±6.49 12.429±2.91 4.488±0.00 4.272±1.98 8.097±3.86 10.443±3.60 15.052±4.85 5.820±1.75 11.760±5.89 13.849±1.39

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001L2 CIL_0001L2_0002 CGP 15:33683876-34142386
CIL_0001KW CIL_0001KW_0002 CGP 15:34082694-34284295

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001085 IEA RNA polymerase II transcription factor binding
GO:0003713 IEA transcription coactivator activity
GO:0003725 ISO double-stranded RNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IEA cytoplasm
GO:0005783 ISS endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005923 IEA tight junction
GO:0010508 IEA positive regulation of autophagy
GO:0016021 IEA integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0016604 IEA nuclear body
GO:0031663 IEA lipopolysaccharide-mediated signaling pathway
GO:0043066 IEA negative regulation of apoptotic process
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044822 IEA poly(A) RNA binding
GO:0045766 IEA positive regulation of angiogenesis
GO:0046581 IEA intercellular canaliculus
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051059 ISS NF-kappaB binding
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0051897 IEA positive regulation of protein kinase B signaling
GO:0070830 IEA tight junction assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000336273 MTDH-001 protein_coding Homo_sapiens 0 4222
ENST00000519934 MTDH-002 protein_coding Homo_sapiens 0 1471
ENST00000521933 MTDH-006 protein_coding Homo_sapiens 0 553
ENST00000522313 MTDH-003 protein_coding Homo_sapiens 0 654
ENST00000598402 RP11-15H20.2-001 processed_pseudogene Homo_sapiens 2e-38 163

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