C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: polo-like kinase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000026858 Plk4-001 ENSMUSG00000025758 10090 + 3:40800019-40816883 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026858
Transcript ID Adipose Adrenal Bladder Brain Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026858 0.365±0.07 0.462±0.16 1.329±0.28 5.136±0.79 0.644±0.24 0.328±0.00 7.332±6.91 0.525±0.05 0.047±0.00 2.041±0.95 7.723±4.29 10.484±5.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007AJ CIL_0007AJ_0002 CGP 3:40744495-40816883
CIL_0007AK CIL_0007AK_0002 CGP 3:40800019-40846885

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005730 IDA nucleolus
GO:0005813 IEA centrosome
GO:0005814 ISS centriole
GO:0006468 IEA protein phosphorylation
GO:0007099 ISS centriole replication
GO:0042802 IPI identical protein binding
GO:0046601 ISO:ISS positive regulation of centriole replication
GO:0060707 IMP trophoblast giant cell differentiation
GO:0098535 IMP de novo centriole assembly
GO:0098536 IDA deuterosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000270861 PLK4-001 protein_coding Homo_sapiens 0 1465
ENST00000503914 PLK4-007 retained_intron Homo_sapiens 0 435
ENST00000507249 PLK4-005 protein_coding Homo_sapiens 0 1814
ENST00000507454 PLK4-011 retained_intron Homo_sapiens 0 455
ENST00000508113 PLK4-009 protein_coding Homo_sapiens 0 390
ENST00000510192 PLK4-010 retained_intron Homo_sapiens 0 580
ENST00000510605 PLK4-008 retained_intron Homo_sapiens 0 455
ENST00000511942 PLK4-006 processed_transcript Homo_sapiens 0 507
ENST00000513090 PLK4-003 protein_coding Homo_sapiens 0 1400
ENST00000514379 PLK4-002 protein_coding Homo_sapiens 0 1358
ENST00000515069 PLK4-004 protein_coding Homo_sapiens 0 1456

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