C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: polo-like kinase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000270861 PLK4-001 ENSG00000142731 9606 + 4:127880861-127899195 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonHeartOvaryPlacentaENST00000270861
Transcript ID Colon Heart Ovary Placenta
ENST00000270861 0.337±0.00 0.023±0.00 0.139±0.00 0.371±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007AJ CIL_0007AJ_0001 CGP 4:127781821-127899195
CIL_0007AK CIL_0007AK_0001 CGP 4:127880861-127965995

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0004672 IEA protein kinase activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005730 ISS nucleolus
GO:0005813 IDA centrosome
GO:0005814 IDA centriole
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0007099 IMP centriole replication
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0042802 IEA identical protein binding
GO:0046601 IMP positive regulation of centriole replication
GO:0060707 ISS trophoblast giant cell differentiation
GO:0098535 ISS de novo centriole assembly
GO:0098536 ISS deuterosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000170825 Plk4-004 protein_coding Mus_musculus 0 1502
ENSMUST00000026858 Plk4-001 protein_coding Mus_musculus 0 1465
ENSMUST00000168363 Plk4-003 retained_intron Mus_musculus 0 1456
ENSMUST00000168287 Plk4-002 protein_coding Mus_musculus 0 1448
ENSMUST00000167556 Plk4-005 protein_coding Mus_musculus 0 1360
ENSMUST00000169566 Plk4-006 protein_coding Mus_musculus 0 438
ENSMUST00000171538 Plk4-007 nonsense_mediated_decay Mus_musculus 0 420
ENSMUST00000166936 Plk4-008 retained_intron Mus_musculus 0 255

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