C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific demethylase 2B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000031435 Kdm2b-009 ENSMUSG00000029475 10090 - 5:122870668-122900355 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000031435
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000031435 7.025±3.34 5.621±0.97 6.046±0.21 27.142±2.72 11.737±2.76 7.400±1.24 2.410±0.08 3.548±0.21 5.929±3.33 6.631±0.32 11.581±3.13 6.860±2.36 8.567±2.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007G4 CIL_0007G4_0003 CGP 5:122850188-123015080
CIL_0007G5 CIL_0007G5_0004 CGP 5:122870668-123030450

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0006351 IEA transcription, DNA-templated
GO:0007283 IMP spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0016577 TAS histone demethylation
GO:0019843 IEA rRNA binding
GO:0021555 IMP midbrain-hindbrain boundary morphogenesis
GO:0021592 IMP fourth ventricle development
GO:0021670 IMP lateral ventricle development
GO:0021678 IMP third ventricle development
GO:0021993 IMP initiation of neural tube closure
GO:0030900 IMP forebrain development
GO:0030901 IMP midbrain development
GO:0030902 IMP hindbrain development
GO:0032452 TAS histone demethylase activity
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0048596 IMP embryonic camera-type eye morphogenesis
GO:0051864 IEA histone demethylase activity (H3-K36 specific)
GO:0055114 IEA oxidation-reduction process
GO:0070544 IEA histone H3-K36 demethylation
GO:2000178 IMP negative regulation of neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000377069 KDM2B-005 protein_coding Homo_sapiens 0 1772
ENST00000377071 KDM2B-001 protein_coding Homo_sapiens 0 3350
ENST00000392464 RNF34-005 protein_coding Homo_sapiens 0 418
ENST00000536036 KDM2B-023 retained_intron Homo_sapiens 0 701
ENST00000536437 KDM2B-201 protein_coding Homo_sapiens 0 547
ENST00000538243 KDM2B-013 retained_intron Homo_sapiens 0 1234
ENST00000538503 KDM2B-020 retained_intron Homo_sapiens 0 1240
ENST00000542973 KDM2B-022 protein_coding Homo_sapiens 0 3049
ENST00000543025 KDM2B-002 nonsense_mediated_decay Homo_sapiens 0 468
ENST00000611216 KDM2B-202 protein_coding Homo_sapiens 0 745

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