C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033468 Arhgef6-001 ENSMUSG00000031133 10090 - X:57231485-57338729 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033468
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033468 2.005±0.75 1.044±0.26 0.299±0.05 3.563±1.58 0.481±0.16 1.713±0.00 1.092±0.16 0.644±0.38 3.410±0.77 2.840±0.00 2.177±1.26 9.436±1.31 0.561±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000JT CIL_0000JT_0002 CGP X:57212143-57338729
CIL_0000PR CIL_0000PR_0003 CGP X:57231485-57393036

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005911 IDA cell-cell junction
GO:0030027 IDA lamellipodium
GO:0030032 IMP lamellipodium assembly
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035556 IEA intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000250617 ARHGEF6-001 protein_coding Homo_sapiens 0 2994
ENST00000370620 ARHGEF6-003 protein_coding Homo_sapiens 0 2549
ENST00000370622 ARHGEF6-002 protein_coding Homo_sapiens 0 2549

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