C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: recombination signal binding protein for immunoglobulin kappa J region
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000037618 Rbpj-201 ENSMUSG00000039191 10090 + 5:53590215-53657445 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonMuscleTestisENSMUST00000037618
Transcript ID Brain Colon Muscle Testis
ENSMUST00000037618 0.458±0.00 0.825±0.00 0.460±0.02 0.393±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000343 CIL_000343_0003 CGP 5:53267106-53657445
CIL_0002TR CIL_0002TR_0003 CGP 5:53555779-53707704

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001077 ISO RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001103 IEA RNA polymerase II repressing transcription factor binding
GO:0001228 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IMP angiogenesis
GO:0001756 TAS somitogenesis
GO:0001837 IMP epithelial to mesenchymal transition
GO:0001947 TAS heart looping
GO:0001974 IMP blood vessel remodeling
GO:0002193 IEA MAML1-RBP-Jkappa- ICN1 complex
GO:0002437 IMP inflammatory response to antigenic stimulus
GO:0003139 IGI secondary heart field specification
GO:0003151 IMP outflow tract morphogenesis
GO:0003157 IMP endocardium development
GO:0003160 IMP endocardium morphogenesis
GO:0003198 IMP epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003214 IMP cardiac left ventricle morphogenesis
GO:0003222 IMP ventricular trabecula myocardium morphogenesis
GO:0003256 IMP regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003677 ISA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005730 IEA nucleolus
GO:0005737 ISS cytoplasm
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006959 IMP humoral immune response
GO:0007219 IMP Notch signaling pathway
GO:0007221 ISS positive regulation of transcription of Notch receptor target
GO:0007507 IMP heart development
GO:0008134 IPI transcription factor binding
GO:0008284 IGI positive regulation of cell proliferation
GO:0008285 IMP negative regulation of cell proliferation
GO:0009912 IMP auditory receptor cell fate commitment
GO:0009957 IMP epidermal cell fate specification
GO:0010468 IMP regulation of gene expression
GO:0010628 IMP positive regulation of gene expression
GO:0021983 IMP pituitary gland development
GO:0030097 IMP hemopoiesis
GO:0030182 IMP neuron differentiation
GO:0030183 IMP B cell differentiation
GO:0030216 IMP keratinocyte differentiation
GO:0030279 IMP negative regulation of ossification
GO:0030513 IMP positive regulation of BMP signaling pathway
GO:0035019 IMP somatic stem cell maintenance
GO:0035481 TAS positive regulation of Notch signaling pathway involved in heart induction
GO:0035912 IMP dorsal aorta morphogenesis
GO:0036302 IMP atrioventricular canal development
GO:0042742 IMP defense response to bacterium
GO:0043011 IMP myeloid dendritic cell differentiation
GO:0043565 IDA sequence-specific DNA binding
GO:0045165 IMP cell fate commitment
GO:0045596 IMP negative regulation of cell differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 ISA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0047485 IPI protein N-terminus binding
GO:0048505 IMP regulation of timing of cell differentiation
GO:0048733 IMP sebaceous gland development
GO:0048820 IMP hair follicle maturation
GO:0060045 IMP positive regulation of cardiac muscle cell proliferation
GO:0060486 IMP Clara cell differentiation
GO:0060716 IMP labyrinthine layer blood vessel development
GO:0060844 IMP arterial endothelial cell fate commitment
GO:0060853 IC Notch signaling pathway involved in arterial endothelial cell fate commitment
GO:0061344 IC regulation of cell adhesion involved in heart morphogenesis
GO:0061371 TAS determination of heart left/right asymmetry
GO:0072554 IMP blood vessel lumenization
GO:0072602 IMP interleukin-4 secretion
GO:0097101 IGI blood vessel endothelial cell fate specification
GO:1901186 IMP positive regulation of ERBB signaling pathway
GO:1901189 IMP positive regulation of ephrin receptor signaling pathway
GO:1901297 IMP positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
GO:2000138 IMP positive regulation of cell proliferation involved in heart morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000342295 RBPJ-201 protein_coding Homo_sapiens 0 2217
ENST00000342320 RBPJ-003 protein_coding Homo_sapiens 0 2065
ENST00000345843 RBPJ-001 protein_coding Homo_sapiens 0 1993
ENST00000348160 RBPJ-030 protein_coding Homo_sapiens 0 1995
ENST00000355476 RBPJ-202 protein_coding Homo_sapiens 0 2065
ENST00000361572 RBPJ-002 protein_coding Homo_sapiens 0 2226
ENST00000411556 RBPJP6-001 processed_pseudogene Homo_sapiens 0 1491
ENST00000442803 RBPJP7-001 processed_pseudogene Homo_sapiens 0 1504
ENST00000449433 RBPJP5-001 processed_pseudogene Homo_sapiens 0 1509
ENST00000504423 RBPJ-026 protein_coding Homo_sapiens 0 387
ENST00000504907 RBPJ-010 protein_coding Homo_sapiens 0 1395
ENST00000504938 RBPJ-020 protein_coding Homo_sapiens 0 693
ENST00000505727 RBPJ-028 retained_intron Homo_sapiens 0 676
ENST00000505958 RBPJ-006 protein_coding Homo_sapiens 1e-21 108
ENST00000506903 RBPJ-025 retained_intron Homo_sapiens 0 514
ENST00000506956 RBPJ-011 protein_coding Homo_sapiens 0 398
ENST00000507561 RBPJ-007 protein_coding Homo_sapiens 0 2063
ENST00000507574 RBPJ-015 protein_coding Homo_sapiens 0 737
ENST00000509158 RBPJ-013 protein_coding Homo_sapiens 0 198
ENST00000510725 RBPJ-027 retained_intron Homo_sapiens 0 425
ENST00000510778 RBPJ-029 protein_coding Homo_sapiens 0 795
ENST00000511401 RBPJ-022 processed_transcript Homo_sapiens 0 204
ENST00000511451 RBPJ-021 retained_intron Homo_sapiens 0 693
ENST00000511546 RBPJ-018 protein_coding Homo_sapiens 0 442
ENST00000512351 RBPJ-004 protein_coding Homo_sapiens 0 383
ENST00000512671 RBPJ-005 protein_coding Homo_sapiens 0 845
ENST00000513182 RBPJ-024 nonsense_mediated_decay Homo_sapiens 0 206
ENST00000514380 RBPJ-009 retained_intron Homo_sapiens 0 1519
ENST00000514675 RBPJ-016 protein_coding Homo_sapiens 0 449
ENST00000514730 RBPJ-014 protein_coding Homo_sapiens 0 464
ENST00000514807 RBPJ-012 protein_coding Homo_sapiens 0 195
ENST00000515023 RBPJ-023 processed_transcript Homo_sapiens 0 206
ENST00000515573 RBPJ-017 protein_coding Homo_sapiens 0 848
ENST00000618187 RP11-120E5.1-001 processed_pseudogene Homo_sapiens 0 1506

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