C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: recombination signal binding protein for immunoglobulin kappa J region
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000345843 RBPJ-001 ENSG00000168214 9606 + 4:26319710-26431066 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000343 CIL_000343_0002 CGP 4:25861830-26435131
CIL_0002TR CIL_0002TR_0002 CGP 4:26163455-26490462

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000150 NAS recombinase activity
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000982 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001103 IPI RNA polymerase II repressing transcription factor binding
GO:0001525 ISS angiogenesis
GO:0001837 ISS epithelial to mesenchymal transition
GO:0002193 IDA MAML1-RBP-Jkappa- ICN1 complex
GO:0003151 ISS outflow tract morphogenesis
GO:0003160 ISS endocardium morphogenesis
GO:0003198 ISS epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003214 ISS cardiac left ventricle morphogenesis
GO:0003222 ISS ventricular trabecula myocardium morphogenesis
GO:0003256 ISS regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003677 TAS:IEA DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA:IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006310 NAS DNA recombination
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007219 IMP Notch signaling pathway
GO:0007221 IDA positive regulation of transcription of Notch receptor target
GO:0010467 TAS gene expression
GO:0030279 ISS negative regulation of ossification
GO:0030513 ISS positive regulation of BMP signaling pathway
GO:0035912 ISS dorsal aorta morphogenesis
GO:0036302 ISS atrioventricular canal development
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0060045 ISS positive regulation of cardiac muscle cell proliferation
GO:0060716 ISS labyrinthine layer blood vessel development
GO:0061314 IC Notch signaling involved in heart development
GO:0072554 ISS blood vessel lumenization
GO:0097101 ISS blood vessel endothelial cell fate specification
GO:1901186 ISS positive regulation of ERBB signaling pathway
GO:1901189 ISS positive regulation of ephrin receptor signaling pathway
GO:2000138 ISS positive regulation of cell proliferation involved in heart morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000087360 Rbpj-202 protein_coding Mus_musculus 0 1995
ENSMUST00000113865 Rbpj-203 protein_coding Mus_musculus 0 1993
ENSMUST00000037618 Rbpj-201 protein_coding Mus_musculus 0 1993
ENSMUST00000182751 Rbpsuh-rs3-001 processed_pseudogene Mus_musculus 0 1930
ENSDART00000092580 rbpjb-001 protein_coding Danio_rerio 0 1024
ENSMUST00000119456 Rbpsuh-ps1-001 processed_pseudogene Mus_musculus 0 931

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