C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000039697 Gabrb3-001 ENSMUSG00000033676 10090 + 7:57591162-57828802 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000039697
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000039697 0.077±0.10 0.408±0.22 0.069±0.03 12.873±2.81 0.008±0.01 0.119±0.03 0.013±0.01 2.187±0.32 0.039±0.02 0.062±0.00 0.006±0.00 0.125±0.05 0.025±0.01 0.199±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006LH CIL_0006LH_0002 CGP 7:57407690-57828802
CIL_0007CV CIL_0007CV_0002 CGP 7:57590518-58829426

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004890 ISS GABA-A receptor activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005254 IEA chloride channel activity
GO:0005886 IDA plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0007214 ISO gamma-aminobutyric acid signaling pathway
GO:0007605 IMP sensory perception of sound
GO:0022851 ISS GABA-gated chloride ion channel activity
GO:0030054 IEA cell junction
GO:0034707 IEA chloride channel complex
GO:0043523 IMP regulation of neuron apoptotic process
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045211 IEA postsynaptic membrane
GO:0048666 IMP neuron development
GO:0060021 IMP palate development
GO:0060119 IMP inner ear receptor cell development
GO:0060384 IMP innervation
GO:0071420 ISS cellular response to histamine
GO:0090102 IMP cochlea development
GO:1901215 IMP negative regulation of neuron death
GO:1902476 ISS chloride transmembrane transport
GO:1902711 ISS GABA-A receptor complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000114750 gabrb2-201 protein_coding Danio_rerio 0 606
ENSDART00000148259 gabrb2-001 protein_coding Danio_rerio 0 597
ENSDART00000087300 gabrb3-001 protein_coding Danio_rerio 0.0000000000001 84
ENST00000299267 GABRB3-001 protein_coding Homo_sapiens 0 3182
ENST00000311550 GABRB3-002 protein_coding Homo_sapiens 0 3469
ENST00000400188 GABRB3-006 protein_coding Homo_sapiens 0 2128
ENST00000541819 GABRB3-003 protein_coding Homo_sapiens 0 3188
ENST00000545868 GABRB3-004 protein_coding Homo_sapiens 0 1808
ENST00000554556 GABRB3-009 nonsense_mediated_decay Homo_sapiens 0 625
ENST00000554722 GABRB3-008 processed_transcript Homo_sapiens 0 263
ENST00000555094 GABRB3-011 protein_coding Homo_sapiens 0 647
ENST00000555632 GABRB3-012 nonsense_mediated_decay Homo_sapiens 0 2126
ENST00000556166 GABRB3-005 nonsense_mediated_decay Homo_sapiens 0 368
ENST00000556636 GABRB3-013 nonsense_mediated_decay Homo_sapiens 3e-35 152
ENST00000557641 GABRB3-010 processed_transcript Homo_sapiens 0 263
ENST00000557765 GABRB3-014 retained_intron Homo_sapiens 0 446
ENST00000622697 GABRB3-201 protein_coding Homo_sapiens 0 2928

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