Gene Ontology |
GO ID | Evidence Type | GO Description |
GO:0000187 |
IMP |
activation of MAPK activity |
GO:0001875 |
ISS |
lipopolysaccharide receptor activity |
GO:0002218 |
IMP |
activation of innate immune response |
GO:0002322 |
IMP |
B cell proliferation involved in immune response |
GO:0002537 |
IMP |
nitric oxide production involved in inflammatory response |
GO:0002755 |
IEA |
MyD88-dependent toll-like receptor signaling pathway |
GO:0004888 |
IEA |
transmembrane signaling receptor activity |
GO:0005515 |
IPI |
protein binding |
GO:0005737 |
IEA |
cytoplasm |
GO:0005886 |
IEA |
plasma membrane |
GO:0005887 |
IEA |
integral component of plasma membrane |
GO:0007250 |
NAS |
activation of NF-kappaB-inducing kinase activity |
GO:0007252 |
IMP |
I-kappaB phosphorylation |
GO:0009617 |
IMP |
response to bacterium |
GO:0009897 |
IEA |
external side of plasma membrane |
GO:0010572 |
IMP |
positive regulation of platelet activation |
GO:0030890 |
IMP |
positive regulation of B cell proliferation |
GO:0031663 |
IDA |
lipopolysaccharide-mediated signaling pathway |
GO:0032496 |
IMP |
response to lipopolysaccharide |
GO:0032497 |
TAS |
detection of lipopolysaccharide |
GO:0032609 |
IGI |
interferon-gamma production |
GO:0032689 |
IMP |
negative regulation of interferon-gamma production |
GO:0032700 |
IMP |
negative regulation of interleukin-17 production |
GO:0032707 |
IMP |
negative regulation of interleukin-23 production |
GO:0032715 |
IMP |
negative regulation of interleukin-6 production |
GO:0032720 |
IMP |
negative regulation of tumor necrosis factor production |
GO:0032722 |
IDA |
positive regulation of chemokine production |
GO:0032727 |
IDA |
positive regulation of interferon-alpha production |
GO:0032728 |
IDA |
positive regulation of interferon-beta production |
GO:0032729 |
IMP |
positive regulation of interferon-gamma production |
GO:0032732 |
IDA |
positive regulation of interleukin-1 production |
GO:0032733 |
IDA |
positive regulation of interleukin-10 production |
GO:0032735 |
IDA |
positive regulation of interleukin-12 production |
GO:0032755 |
IMP |
positive regulation of interleukin-6 production |
GO:0032757 |
IEA |
positive regulation of interleukin-8 production |
GO:0032760 |
IMP |
positive regulation of tumor necrosis factor production |
GO:0032874 |
IDA |
positive regulation of stress-activated MAPK cascade |
GO:0034142 |
IEA |
toll-like receptor 4 signaling pathway |
GO:0042116 |
ISS |
macrophage activation |
GO:0042346 |
IEA |
positive regulation of NF-kappaB import into nucleus |
GO:0042535 |
IEA |
positive regulation of tumor necrosis factor biosynthetic process |
GO:0043123 |
IDA |
positive regulation of I-kappaB kinase/NF-kappaB signaling |
GO:0045084 |
IEA |
positive regulation of interleukin-12 biosynthetic process |
GO:0045087 |
TAS |
innate immune response |
GO:0045348 |
IMP |
positive regulation of MHC class II biosynthetic process |
GO:0045359 |
IMP |
positive regulation of interferon-beta biosynthetic process |
GO:0045362 |
NAS |
positive regulation of interleukin-1 biosynthetic process |
GO:0045368 |
NAS |
positive regulation of interleukin-13 biosynthetic process |
GO:0045410 |
NAS |
positive regulation of interleukin-6 biosynthetic process |
GO:0045416 |
IEA |
positive regulation of interleukin-8 biosynthetic process |
GO:0045429 |
IMP |
positive regulation of nitric oxide biosynthetic process |
GO:0045576 |
NAS |
mast cell activation |
GO:0045944 |
IDA |
positive regulation of transcription from RNA polymerase II promoter |
GO:0046330 |
IDA |
positive regulation of JNK cascade |
GO:0046696 |
ISS |
lipopolysaccharide receptor complex |
GO:0048471 |
IEA |
perinuclear region of cytoplasm |
GO:0050671 |
IMP |
positive regulation of lymphocyte proliferation |
GO:0050707 |
IEA |
regulation of cytokine secretion |
GO:0050727 |
IMP |
regulation of inflammatory response |
GO:0050829 |
IMP |
defense response to Gram-negative bacterium |
GO:0051092 |
IEA |
positive regulation of NF-kappaB transcription factor activity |
GO:0051770 |
IDA |
positive regulation of nitric-oxide synthase biosynthetic process |
GO:0060729 |
IMP |
intestinal epithelial structure maintenance |
GO:0060907 |
IMP |
positive regulation of macrophage cytokine production |
GO:0070373 |
IMP |
negative regulation of ERK1 and ERK2 cascade |
GO:0070374 |
IDA |
positive regulation of ERK1 and ERK2 cascade |
GO:0070430 |
IDA |
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway |
GO:0070434 |
IDA |
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway |
GO:0071222 |
IDA |
cellular response to lipopolysaccharide |
GO:0071223 |
IMP |
cellular response to lipoteichoic acid |
GO:0071260 |
IEA |
cellular response to mechanical stimulus |