C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sodium channel, voltage-gated, type XI, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000070617 Scn11a-201 ENSMUSG00000034115 10090 - 9:119753763-119825456 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000070617
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000070617 0.011±0.00 0.011±0.00 0.061±0.00 0.046±0.03 0.211±0.07 0.019±0.01 0.016±0.00 0.008±0.00 0.023±0.01 0.010±0.01 0.020±0.01 0.009±0.01 0.118±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BE CIL_0008BE_0002 VISTA 9:119196374-119798584
CIL_0004RE CIL_0004RE_0002 CGP 9:119608456-119825456
CIL_0006H1 CIL_0006H1_0002 CGP 9:119753763-119926579

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0005248 IDA voltage-gated sodium channel activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0006814 IDA sodium ion transport
GO:0019228 IBA neuronal action potential
GO:0030424 IDA axon
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0044299 IDA C-fiber
GO:0051930 IMP regulation of sensory perception of pain
GO:0070062 IEA extracellular vesicular exosome
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000011718 scn1a-201 protein_coding Danio_rerio 0 198
ENSDART00000090979 scn1a-202 protein_coding Danio_rerio 0 198
ENST00000283256 SCN2A-001 protein_coding Homo_sapiens 9e-37 161
ENST00000302328 SCN11A-001 protein_coding Homo_sapiens 0 1688
ENST00000375427 SCN2A-002 protein_coding Homo_sapiens 7e-37 161
ENST00000375437 SCN2A-201 protein_coding Homo_sapiens 9e-37 161
ENST00000444237 SCN11A-002 protein_coding Homo_sapiens 0 1585
ENST00000456224 SCN11A-003 protein_coding Homo_sapiens 0 1652

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