C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin beta 1 (fibronectin receptor beta)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000090006 Itgb1-001 ENSMUSG00000025809 10090 + 8:128685654-128733200 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000090006
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000090006 46.059±2.45 19.752±3.35 202.938±7.81 20.019±9.56 29.303±6.14 25.956±10.49 55.361±4.25 39.253±7.40 33.005±11.58 63.201±8.28 33.396±1.17 49.274±28.51 101.331±22.52 5.018±0.96

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000CP CIL_0000CP_0002 CGP 8:128359073-128733200

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0001669 IEA acrosomal vesicle
GO:0001701 IMP in utero embryonic development
GO:0001708 IMP cell fate specification
GO:0001894 IEA tissue homeostasis
GO:0001948 IEA glycoprotein binding
GO:0001968 IEA fibronectin binding
GO:0002020 IEA protease binding
GO:0002042 IMP cell migration involved in sprouting angiogenesis
GO:0003779 IEA actin binding
GO:0004872 IEA receptor activity
GO:0005102 IEA receptor binding
GO:0005178 IPI integrin binding
GO:0005515 IPI protein binding
GO:0005518 IEA collagen binding
GO:0005604 IEA basement membrane
GO:0005737 IEA cytoplasm
GO:0005768 IEA endosome
GO:0005886 IDA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005912 IEA adherens junction
GO:0005925 IEA focal adhesion
GO:0006874 IEA cellular calcium ion homeostasis
GO:0007155 IEA cell adhesion
GO:0007159 IEA leukocyte cell-cell adhesion
GO:0007160 IGI cell-matrix adhesion
GO:0007161 IEA calcium-independent cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008277 IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0008284 IMP positive regulation of cell proliferation
GO:0008285 IEA negative regulation of cell proliferation
GO:0008354 IMP germ cell migration
GO:0008542 IGI visual learning
GO:0009897 IDA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0010710 ISS regulation of collagen catabolic process
GO:0010811 IEA positive regulation of cell-substrate adhesion
GO:0010976 IEA positive regulation of neuron projection development
GO:0014704 IDA intercalated disc
GO:0014823 IEA response to activity
GO:0016477 IMP cell migration
GO:0019900 IEA kinase binding
GO:0019901 IEA protein kinase binding
GO:0019904 IEA protein domain specific binding
GO:0021943 IMP formation of radial glial scaffolds
GO:0030056 IEA hemidesmosome
GO:0030175 IEA filopodium
GO:0030335 IEA positive regulation of cell migration
GO:0031175 IMP neuron projection development
GO:0031345 IEA negative regulation of cell projection organization
GO:0031589 IEA cell-substrate adhesion
GO:0031594 IDA neuromuscular junction
GO:0031667 IEA response to nutrient levels
GO:0032403 IEA protein complex binding
GO:0032594 IEA protein transport within lipid bilayer
GO:0033631 IEA cell-cell adhesion mediated by integrin
GO:0034113 IEA heterotypic cell-cell adhesion
GO:0034665 IEA integrin alpha1-beta1 complex
GO:0034666 IEA integrin alpha2-beta1 complex
GO:0034667 IEA integrin alpha3-beta1 complex
GO:0034677 IPI integrin alpha7-beta1 complex
GO:0034679 IEA integrin alpha9-beta1 complex
GO:0034680 IEA integrin alpha10-beta1 complex
GO:0034681 IEA integrin alpha11-beta1 complex
GO:0034698 IEA response to gonadotropin
GO:0035024 IGI negative regulation of Rho protein signal transduction
GO:0035748 IDA myelin sheath abaxonal region
GO:0042277 IEA peptide binding
GO:0042383 IDA sarcolemma
GO:0042493 IEA response to drug
GO:0043065 IEA positive regulation of apoptotic process
GO:0043197 IDA dendritic spine
GO:0043235 ISO receptor complex
GO:0043236 IDA laminin binding
GO:0043410 IEA positive regulation of MAPK cascade
GO:0045121 IEA membrane raft
GO:0045202 IDA synapse
GO:0045214 IMP sarcomere organization
GO:0045596 IMP negative regulation of cell differentiation
GO:0045665 IEA negative regulation of neuron differentiation
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045807 IEA positive regulation of endocytosis
GO:0046872 IEA metal ion binding
GO:0046982 ISS protein heterodimerization activity
GO:0048333 IEA mesodermal cell differentiation
GO:0048675 IGI axon extension
GO:0048738 IMP cardiac muscle tissue development
GO:0048813 IGI dendrite morphogenesis
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050839 IEA cell adhesion molecule binding
GO:0050901 IEA leukocyte tethering or rolling
GO:0051393 IEA alpha-actinin binding
GO:0051726 IMP regulation of cell cycle
GO:0055007 IMP cardiac muscle cell differentiation
GO:0060135 IEA maternal process involved in female pregnancy
GO:0070062 IEA extracellular vesicular exosome
GO:0070830 IEA tight junction assembly
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071305 IEA cellular response to vitamin D
GO:0071438 ISS invadopodium membrane
GO:0071479 IEA cellular response to ionizing radiation
GO:0071559 IEA response to transforming growth factor beta
GO:0090004 ISS positive regulation of establishment of protein localization to plasma membrane
GO:0097060 IDA synaptic membrane
GO:0098639 IEA collagen binding involved in cell-matrix adhesion
GO:2000811 IEA negative regulation of anoikis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000302278 ITGB1-001 protein_coding Homo_sapiens 0 3025
ENST00000396033 ITGB1-201 protein_coding Homo_sapiens 0 3018
ENST00000414670 ITGB1-002 protein_coding Homo_sapiens 1.99965e-42 176
ENST00000417122 ITGB1-003 protein_coding Homo_sapiens 0 320
ENST00000423113 ITGB1-202 protein_coding Homo_sapiens 0 2726
ENST00000437302 ITGB1-006 protein_coding Homo_sapiens 0 460
ENST00000464001 ITGB1-008 retained_intron Homo_sapiens 0 278
ENST00000472147 ITGB1-013 protein_coding Homo_sapiens 0 215
ENST00000474568 ITGB1-004 protein_coding Homo_sapiens 0 468
ENST00000475184 ITGB1-012 protein_coding Homo_sapiens 0 418
ENST00000480226 ITGB1-009 protein_coding Homo_sapiens 0 542
ENST00000484088 ITGB1-011 processed_transcript Homo_sapiens 0 427
ENST00000488427 ITGB1-005 protein_coding Homo_sapiens 0 311
ENST00000488494 ITGB1-010 protein_coding Homo_sapiens 0 475
ENST00000493758 ITGB1-007 protein_coding Homo_sapiens 0 274
ENST00000494395 ITGB1-014 nonsense_mediated_decay Homo_sapiens 0 381
ENST00000528877 ITGB1-015 protein_coding Homo_sapiens 0 375
ENST00000534049 ITGB1-016 protein_coding Homo_sapiens 0 472
ENST00000596032 ITGB1P1-001 processed_pseudogene Homo_sapiens 0 710

Loading