C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SMAD family member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000091831 Smad2-003 ENSMUSG00000024563 10090 + 18:76241701-76304730 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000091831
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000091831 4.548±0.00 5.429±1.84 6.828±4.28 2.160±0.00 3.289±0.63 1.982±1.05 2.359±0.32 1.535±0.58 1.962±0.00 0.786±0.08 11.690±10.26 28.600±12.77 6.037±4.57

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008EL CIL_0008EL_0002 VISTA 18:75860386-76461964
CIL_0008FI CIL_0008FI_0002 VISTA 18:75921908-76522726

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001657 IEP ureteric bud development
GO:0001701 IGI in utero embryonic development
GO:0001706 IMP endoderm formation
GO:0001707 IMP mesoderm formation
GO:0003682 IDA chromatin binding
GO:0003690 IDA double-stranded DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0007182 ISO common-partner SMAD protein phosphorylation
GO:0007369 IGI gastrulation
GO:0007389 IGI pattern specification process
GO:0007492 IGI endoderm development
GO:0007507 IGI heart development
GO:0008134 IPI transcription factor binding
GO:0009749 IGI response to glucose
GO:0009791 IGI post-embryonic development
GO:0009880 IGI embryonic pattern specification
GO:0009952 IMP anterior/posterior pattern specification
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0010718 IMP positive regulation of epithelial to mesenchymal transition
GO:0030073 IGI insulin secretion
GO:0030324 IGI lung development
GO:0031016 IGI pancreas development
GO:0035265 IGI organ growth
GO:0035556 IDA intracellular signal transduction
GO:0045165 IMP cell fate commitment
GO:0045893 IDA:IMP positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046332 IPI SMAD binding
GO:0046872 IEA metal ion binding
GO:0048340 IMP paraxial mesoderm morphogenesis
GO:0048589 IGI developmental growth
GO:0048617 IGI embryonic foregut morphogenesis
GO:0048701 IGI embryonic cranial skeleton morphogenesis
GO:0051098 IDA regulation of binding
GO:0060021 IMP palate development
GO:0060039 IGI pericardium development
GO:0060395 IGI SMAD protein signal transduction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000044756 smad2-201 protein_coding Danio_rerio 0 808
ENSDART00000128579 smad2-202 protein_coding Danio_rerio 0 800
ENSDART00000147653 smad2-002 protein_coding Danio_rerio 0 800
ENSDART00000121892 smad2-001 protein_coding Danio_rerio 0 800
ENST00000262160 SMAD2-001 protein_coding Homo_sapiens 0 1496
ENST00000356825 SMAD2-201 protein_coding Homo_sapiens 0 2061
ENST00000402690 SMAD2-002 protein_coding Homo_sapiens 0 1496
ENST00000585978 SMAD2-009 protein_coding Homo_sapiens 0 375
ENST00000586040 SMAD2-004 protein_coding Homo_sapiens 0 1868
ENST00000586514 SMAD2-005 protein_coding Homo_sapiens 0 414
ENST00000587269 SMAD2-008 protein_coding Homo_sapiens 0 414
ENST00000587353 SMAD2-011 processed_transcript Homo_sapiens 0 418
ENST00000587421 SMAD2-007 protein_coding Homo_sapiens 0 375
ENST00000589877 SMAD2-006 protein_coding Homo_sapiens 0 375
ENST00000591214 SMAD2-003 protein_coding Homo_sapiens 0 1679

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